59924

Polysorbate 80

tested according to Ph. Eur.

• Synonym(s): TWEEN^® 80, Polysorbatum 80, POE (20) sorbitan monooleate, Polyethylene glycol sorbitan monooleate, Polyoxyethylenesorbitan monooleate, Polysorbate 80
• CAS Number: 9005-65-6
• Número MDL: MFCD00082107
• NACRES: NA.21

Properties

• Agency: USP/NF; tested according to Ph. Eur.
• Nível de qualidade: 200
• pressão de vapor: <1 mmHg ( 20 °C)
• descrição: non-ionic
• forma: liquid
• peso molecular: average mol wt 79,000
• número de agregação: 60
• índice de refração: n20/D 1.472 (lit.)
• CMC: 0.012
• temperatura de transição: cloud point 65 °C
• densidade: 1.064 g/mL at 25 °C (lit.)
• HLB: 15
• application(s): pharmaceutical (small molecule)
• InChI: 1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-27-29(39-22-19-34)32-28(38-21-18-33)26-31(42-32)41-23-20-35/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+
• InChI key: RGPBUVUVZKQNHD-MDZDMXLPSA-N

Description

Descrição geral

Polysorbate 80 is a surfactant. Polysorbates are a combination of oleic esters of sorbitol and sorbitanes with polyethylene glycol chains.

Aplicação

Polysorbate 80 has been used in drug (rapamycin) treatment and to study the effect of rapamycin on osteolysis and tumor growth. It has also been used in the preparation of spray-dried emulsions and to study antibacterial efficacy.

Embalagem

100 g

1 kg

Ações bioquímicas/fisiológicas

Polysorbates is used as emulsifiers, dissolving agents and stabilizer for essential oils, topical application and medical infusions including intravenous, subcutaneous or intramuscular administration.

Informações legais

TWEEN is a registered trademark of Croda International PLC

Safety Information

• Código de classe de armazenamento: 10 - Combustible liquids
• WGK: WGK 1
• Ponto de fulgor (ºF): Not applicable
• Ponto de fulgor (ºC): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves