63560

Millipore

D-Mannitol

ACS reagent, suitable for microbiology, ≥99.0%

Sinônimo(s):
Mannite
Empirical Formula (Hill Notation):
C6H14O6
Número CAS:
Peso molecular:
182.17
Beilstein/REAXYS Number:
1721898
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.74

Nível de qualidade

200

grau

ACS reagent

teor

≥99.0% (sum of enantiomers, HPLC)
≥99.0%

forma

powder

atividade óptica

[α]20/D +24.0±1° in borax solution acc. to ACS

aplicação(ões)

microbiology: suitable (preparation)

resíduo de ignição

≤0.01% (as SO4)

perda

≤0.05% loss on drying, 20 °C (HV)

pf

165-169 °C
167-170 °C (lit.)

solubilidade

H2O: 0.1 g/mL, clear, colorless

traços de ânion

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

traços de cátion

As: ≤0.1 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg
heavy metals: ≤5 ppm (by ICP-OES)

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1

InChI key

FBPFZTCFMRRESA-KVTDHHQDSA-N

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Descrição geral

D-Mannitol is a hexose present in plants, bacteria, algae, and fungi.

Aplicação

D-Mannitol has been used as a component of soya flour mannitol (SFM) medium for culturing Streptomyces.

Ações bioquímicas/fisiológicas

D-Mannitol finds application in the food and pharmaceutical industry. The interaction of mannitol with neutrophils and monocytes is correlated to the upregulation of immune markers. Mannitol acts as a free-radical scavenger and may be beneficial during ischemia-reperfusion injury. It possesses osmotic diuretic properties and may help in managing cerebral edema and high intracranial pressure (ICP).
A sugar alcohol sweet tastant. Used in sweetness inhibition studies.

Outras notas

Important starting material for the synthesis of many chiral building blocks.

storage_class_code

11 - Combustible Solids

WGK Alemanha

WGK 2

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificado de análise

Certificado de origem

Matthias Turina et al.
Inflammation, 31(2), 74-83 (2007-10-25)
D-Mannitol is a substance widely used for both clinical applications as a strong diuretic and in basic research as a purportedly inert osmotic control substance. However, recent experiments have shown that mannitol is able to decrease neutrophil apoptosis in vitro...
S. Hanessian
Total Synthesis of Natural Products: The Chiron Approach (1983)
Rapid Nitrate Reduction Assay with Intact Microbial Cells or Spores
Fischer M, et al.
Bio-protocol, 4(12) (4)
Mannitol: a review of its clinical uses
Shawkat H, et al.
Continuing education in anaesthesia, critical care & pain, 12(2) (12)
Determination of Oxygen Respiration Rates in Wetted Developmentally Arrested Spores of Streptomyces Species
Fischer M, et al.
Bio-protocol, 4(12) (4)

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