Merck
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81845

Sigma-Aldrich

Propidium iodide

≥94% (HPLC)

Sinônimo(s):
3,8-Diamino-5-[3-(diethylmethylammonio)propyl]-6-phenylphenanthridinium diiodide
Empirical Formula (Hill Notation):
C27H34I2N4
Número CAS:
Peso molecular:
668.39
Beilstein:
3843838
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.77

Nível de qualidade

200

teor

≥94% (HPLC)

forma

powder

pf

220-225 °C (dec.) (lit.)

fluorescência

λex 482 nm; λem 608 nm (pH 7.2)
λex 540 nm; λem 608 nm (bound to DNA)

temperatura de armazenamento

2-8°C

SMILES string

[I-].[I-].CC[N+](C)(CC)CCC[n+]1c(-c2ccccc2)c3cc(N)ccc3c4ccc(N)cc14

InChI

1S/C27H33N4.2HI/c1-4-31(3,5-2)17-9-16-30-26-19-22(29)13-15-24(26)23-14-12-21(28)18-25(23)27(30)20-10-7-6-8-11-20;;/h6-8,10-15,18-19,29H,4-5,9,16-17,28H2,1-3H3;2*1H/q+1;;/p-1

InChI key

XJMOSONTPMZWPB-UHFFFAOYSA-M

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Descrição geral

Propidium iodide is a fluorescent intercalating agent used for staining. It functions as an apoptosis marker and has linear DNA-binding capacity. Propidium iodide is an effective indicator of tissue injury.
PI is used for selective labelling of dead cells.

Aplicação

in scrape-loading dye transfer assay
Propidium iodide has been used:
  • to stain DNA in cell cycle analysis
  • to stain cells and cell nuclei
  • for the preparation of propidium iodide (PI)stock solution
  • to stain cells for flow cytometry

Embalagem

25, 100 mg in glass bottle
Bottomless glass bottle. Contents are inside inserted fused cone.

Características e benefícios

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Pictogramas

Health hazard

Palavra indicadora

Warning

Frases de perigo

Classificações de perigo

Muta. 2

Código de classe de armazenamento

11 - Combustible Solids

WGK

WGK 3

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Certificado de análise

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Certificado de origem

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Mais documentos

Cotações e pedidos

Intramolecular loop/tail interactions are essential for connexin 43-hemichannel activity
Ponsaerts R, et al.
Faseb Journal, 24(11), 4378-4395 (2010)
Intravital microscopic methods to evaluate anti-inflammatory effects and signaling mechanisms evoked by hydrogen sulfide
Methods in Enzymology, 555, 93-125 (2015)
Flow cytometry (2008)
Effect of Different Combinations of the Growth Factors and Hormones on invitro Maturation of Goat Preantral Follicles
Shankaraiah P, et al.
International Journal of Current Microbiology and Applied Sciences, 7(4), 1956-1963 (2018)
High-throughput, non-perturbing quantification of lipid droplets with Digital Holographic Microscopy
Campos V, et al.
Journal of Lipid Research, jlr-D085217 (2018)

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