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95212

Sigma-Aldrich

Ácido L-ascórbico

tested according to Ph. Eur.

Sinônimo(s):
Ácido L-treoascórbico, Fator antiescorbútico, Vitamina C
Empirical Formula (Hill Notation):
C6H8O6
Número CAS:
Peso molecular:
176.12
Beilstein:
84272
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.21

fonte biológica

synthetic

Nível de qualidade

Agency

USP/NF
tested according to Ph. Eur.

Ensaio

99.0-100.5%

forma

solid

cor

white to off-white

pH

1.0-2.5 (25 °C, 176 g/L in water)

pf

190-194 °C (dec.)

solubilidade

water: soluble 176 g/L at 20 °C

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Gene Information

human ... SLC23A2(9962)

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Este Item
A2218A596095209
L-Ascorbic acid tested according to Ph. Eur.

Sigma-Aldrich

95212

L-Ascorbic acid

L-Ascorbic acid meets USP testing specifications

Sigma-Aldrich

A2218

L-Ascorbic acid

L-Ascorbic acid BioXtra, ≥99.0%, crystalline

Sigma-Aldrich

A5960

L-Ascorbic acid

L-Ascorbic acid BioUltra, ≥99.5% (RT)

Sigma-Aldrich

95209

L-Ascorbic acid

assay

99.0-100.5%

assay

99.0-100.5%

assay

≥99.0%

assay

≥99.5% (RT)

form

solid

form

solid

form

crystalline

form

powder or crystals

color

white to off-white

color

-

color

white to off-white

color

white to off-white

mp

190-194 °C (dec.)

mp

190-194 °C (dec.)

mp

190-194 °C (dec.)

mp

190-194 °C (dec.)

solubility

water: soluble 176 g/L at 20 °C

solubility

water: soluble 176 g/L at 20 °C

solubility

H2O: 0.5 M, clear, colorless

solubility

H2O: 1 M at 20 °C, clear, colorless

Descrição geral

L-Ascorbic acid is the most biologically active form of ascorbic acid. It is hydrophilic and an unstable compound. L-Ascorbic acid contains a six-carbon lactone produced by plants and some animal species but not by humans and other primates. Ascorbic acid, also referred to as Vitamin C, is a water-soluble vitamin. Ascorbic acid carries a neutral charge, which gets converted to ascorbate by protonation. Vitamin C is a part of citrus fruits, such as broccoli, strawberries, turnip.

Ações bioquímicas/fisiológicas

L-Ascorbic acid functions according to its oxido-reduction property. It is a co-factor for hydroxylation. The biochemical actions of L-ascorbic acid is dependent on the activity of monoxygenase. It is involved in carnitine, collagen synthesis and production of neurotransmitters. Vitamin C exhibits anti-oxidant properties. Vitamin C plays a role in providing protection against photoaging and anti-aging effect. Deficiency of vitamin C leads to scurvy, bleeding gums, poor wound healing, anemia and muscle degeneration.
Ascorbic Acid, also known as Vitamin C, is a six-carbon lactone produced by plants and some animal species but not by humans and other primates.

Código de classe de armazenamento

11 - Combustible Solids

WGK

WGK 1

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

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L-Ascorbic acid analytical standard

Supelco

47863

L-Ascorbic acid

L-Ascorbic acid ACS reagent, ≥99%

Sigma-Aldrich

255564

L-Ascorbic acid

L-Ascorbic acid powder, suitable for cell culture, γ-irradiated

Sigma-Aldrich

A4403

L-Ascorbic acid

Sodium acetate puriss. p.a., ACS reagent, reag. Ph. Eur., anhydrous

Sigma-Aldrich

32319

Sodium acetate

Ascorbic Acid Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1008

Ascorbic Acid

L-Ascorbic acid anhydrous, free-flowing, Redi-Dri™, ACS reagent, ≥99%

Sigma-Aldrich

795437

L-Ascorbic acid

L-Ascorbic acid reagent grade

Sigma-Aldrich

A0278

L-Ascorbic acid

1,2-Propanediol meets analytical specification of Ph. Eur., BP, USP, ≥99.5%

Sigma-Aldrich

16033

1,2-Propanediol

L-Ascorbic acid reagent grade, crystalline

Sigma-Aldrich

A7506

L-Ascorbic acid

Topical vitamin C and the skin: mechanisms of action and clinical applications
Al-Niaimi F and Chiang N Y Z
The Journal of Clinical and Aesthetic Dermatology, 10(7), 14-14 (2017)
Vitamin C in health and disease: its role in the metabolism of cells and redox state in the brain
Figueroa M R and Rivas A S
Frontiers in Physiology, 6(4), 397-397 (2015)
Vitamin C in disease prevention and cure: an overview
Chambial S, et al.
Indian Journal of Clinical Biochemistry : IJCB, 28(4), 314-328 (2013)
Takashi Yoshida et al.
Nature chemical biology, 2(11), 596-607 (2006-09-26)
Transient receptor potential (TRP) proteins form plasma-membrane cation channels that act as sensors for diverse cellular stimuli. Here, we report a novel activation mechanism mediated by cysteine S-nitrosylation in TRP channels. Recombinant TRPC1, TRPC4, TRPC5, TRPV1, TRPV3 and TRPV4 of
Christopher Grunseich et al.
Neurobiology of disease, 70, 12-20 (2014-06-14)
Spinal and bulbar muscular atrophy (SBMA, Kennedy's disease) is a motor neuron disease caused by polyglutamine repeat expansion in the androgen receptor. Although degeneration occurs in the spinal cord and muscle, the exact mechanism is not clear. Induced pluripotent stem

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