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A1300000

Ascorbic acid

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):
L-Ascorbic acid, Antiscorbutic factor, Vitamin C, L-Threoascorbic acid
Empirical Formula (Hill Notation):
C6H8O6
Número CAS:
Peso molecular:
176.12
Beilstein:
84272
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.24

fonte biológica

synthetic

grau

pharmaceutical primary standard

Agency

EP Reference standard

forma

solid

manufacturer/tradename

EDQM

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

pf

190-194 °C (dec.)

application(s)

pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

2-8°C

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Ascorbic acid or vitamin C is a water-soluble vitamin found in various foodstuffs. The benefits of vitamin C may include protection against immune system deficiencies and cardiovascular disease, hyperpigmentation treatment, skin protection, anti-aging, iron absorption, and RBC production. It is used to treat scurvy, and it also functions as an antioxidant. Vitamin C is useful in the biosynthesis of collagen, L-carnitine, and neurotransmitters.

Aplicação

Ascorbic acid may be used as an analytical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography and spectrophotometric techniques.

Embalagem

Unit quantity: 70 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Atenção

Outras notas

Sales restrictions may apply.

Código de classe de armazenamento

13 - Non Combustible Solids

WGK

WGK 1

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Certificado de análise

Insira o número de lote para pesquisar o Certificado de análise (COA).

Certificado de origem

Insira o número de lote para pesquisar o Certificado de origem (COO).

Mais documentos

Quotes and Ordering

Spectrophotometric determination of L-ascorbic acid in pharmaceuticals
Szpikowska-Sroka B and Poledniok J
Journal of Analytical Chemistry, 66(10), 941-941 (2011)
Reversed-phase ion-pair HPLC determination of some water-soluble vitamins in pharmaceuticals
Ivanovic D, et al.
Journal of Pharmaceutical and Biomedical Analysis, 18(6), 999-1004 (1999)
Ascorbic acid
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 18(6), 6868-6869 (2019)
Vitamin C: One compound, several uses. Advances for delivery, efficiency and stability
Carita AC, et al.
Nanomedicine: Nanotechnology, Biology, and Medicine, 31(2), 102117-102117 (2019)
First bioarchaeological evidence of probable scurvy in Southeast Asia: multifactorial etiologies of vitamin C deficiency in a tropical environment
Halcrow SE, et al.
International Journal of Paleopathology, 5(1), 63-71 (2014)

Protocolos

HPLC Analysis of Ascorbic Acid on Ascentis® RP-Amide

Separation of (L)-Dehydroascorbic acid; L-Ascorbic acid 20 μg/mL

HPLC Analysis of Vitamins, Water Soluble on Discovery® C18

Separation of Pyridoxine; Nicotinamide; Nicotinic acid; Folic acid; (−)-Riboflavin, meets USP testing specifications; L-Ascorbic acid

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