Merck
All Photos(9)

B4501

Sigma-Aldrich

Biotin

≥99% (HPLC), lyophilized powder

Synonym(s):
D-Biotin, Bios II, Coenzyme R, Vitamin B7, Vitamin H
Empirical Formula (Hill Notation):
C10H16N2O3S
CAS Number:
Molecular Weight:
244.31
Beilstein:
86838
Número EC:
Número MDL:
eCl@ss:
34058011
ID de substância PubChem:
NACRES:
NA.21

fonte biológica

synthetic (organic)

Nível de qualidade

300

teor

≥99% (HPLC)

forma

lyophilized powder

technique(s)

HPLC: suitable

cor

white to off-white

pf

231-233 °C (lit.)

solubilidade

ammonium hydroxide: 50 mg/mL (2 M)

temperatura de armazenamento

2-8°C

SMILES string

[H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2

InChI

1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1

InChI key

YBJHBAHKTGYVGT-ZKWXMUAHSA-N

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Aplicação

Biotin may be used to elute proteins from avidin/streptavidin resins.
  • It has been used for culturing of oligodendrocytes.
  • It has been used as a vitamin supplement for the growth of Bacillus species.
  • It has been used for blocking endogenous biotin during immunohistology procedures.

Embalagem

100, 500 mg in poly bottle
1, 5, 10, 25 g in poly bottle

Ações bioquímicas/fisiológicas

Biotin is a small molecule and its presence with biologically active macromolecules does not affect the biological function of the macromolecule. The biotin-(strept)avidin system are required for various applications. Biotin also works as a cofactor of carboxylating enzymes, such as pyruvate carboxylase. It catalyzes the formation of oxaloacetate from pyruvate and CO2. Biotin conjugation with avidin or streptavidin helps in linking the target molecule (antibody, nucleotide, protein A etc.) with the labeling system (enzyme, fluorescent, chemiluminescent probes). This complex is used for many detection systems, such as immunoassays, DNA hybridization assays, immunohistochemistry and flow-cytometry. This approach is also applied for the purification and characterization of various molecules of interest.

Código de classe de armazenamento

11 - Combustible Solids

WGK

WGK 1

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificate of Analysis

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Certificate of Origin

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