Merck
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D1435

Sigma-Aldrich

Dimethyl sulfoxide

meets EP testing specifications, meets USP testing specifications

Synonym(s):
DMSO
Linear Formula:
(CH3)2SO
CAS Number:
Molecular Weight:
78.13
Beilstein:
506008
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.71

Agency

meets EP testing specifications
meets USP testing specifications

Nível de qualidade

200

densidade de vapor

2.7 (vs air)

pressão de vapor

0.42 mmHg ( 20 °C)

teor

≥99.5%

forma

liquid

temperatura de autoignição

573 °F

Lim. expl.

42 %, 63 °F

technique(s)

cryopreservation: suitable

Impurezas

≤0.1% water (Karl Fischer, USP)
≤0.2% water (Karl Fischer, EP)

cor

colorless

índice de refração

n20/D 1.478-1.479
n20/D 1.479 (lit.)

pb

189 °C (lit.)

pf

16-19 °C (lit.)

solubilidade

H2O: miscible (completely)

densidade

1.100-1.104 g/mL at 25 °C (relative density (EP))
1.10 g/mL (lit.)

Absorção UV

λ: 285 nm Amax: ≤0.20
λ: 295 nm Amax: ≤0.20

SMILES string

CS(C)=O

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

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Aplicação

Dimethyl sulfoxide has been used:
  • for the dissolution of tetramethylrhodamine dye, which is used as fluorophore for fluorescence in- situ hybridization (FISH) experiments[1]
  • as a control in indirect immunofluorescent assay (IFA) of swine testicular (ST) cells[2]
  • for the suspension and separation of buccal cells[3]
  • a polar aprotic solvent used in polymerase chain reactions (PCR) and as a cryoprotectant vitrification agent for the preservation of cells, tissues and organs.

Embalagem

500 mL in glass bottle
1 L in glass bottle

Ações bioquímicas/fisiológicas

Dimethyl sulfoxide (DMSO) is a low molecular weight, less hydrophilic and a freely permeable cryoprotectant.[4] It is a polar aprotic solvent used in polymerase chain reactions (PCR) and as a cryoprotectant and vitrification agent for the preservation of cells, tissues and organs.[5]

Atenção

Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.

Outras notas

For information on dimethyl sulfoxide miscibility, please visit the following link:
Dimethyl Sulfoxide Miscibility/Immiscibility Table

Código de classe de armazenamento

10 - Combustible liquids

WGK

WGK 1

Ponto de fulgor (ºF)

188.6 °F - closed cup

Ponto de fulgor (ºC)

87 °C - closed cup

Equipamento de proteção individual

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Certificate of Analysis

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Certificate of Origin

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