E9884

Sigma-Aldrich

Ethylenediaminetetraacetic acid

ACS reagent, 99.4-100.6%, powder

Sinônimo(s):
Edathamil, (Ethylenedinitrilo)tetraacetic acid, EDTA, Ethylenedinitrilotetraacetic acid
Fórmula linear:
(HO2CCH2)2NCH2CH2N(CH2CO2H)2
Número CAS:
Peso molecular:
292.24
Beilstein/REAXYS Number:
1716295
Número EC:
Número MDL:
eCl@ss:
39030907
ID de substância PubChem:
NACRES:
NA.77

Nível de qualidade

200

grau

ACS reagent

teor

99.4-100.6%

forma

powder

Impurezas

≤0.005% Insol. dil. NH4OH
≤0.1% Nitrilotriacetic acid ([HOCOCH2]3N)

resíduo de ignição

≤0.2%

pf

250 °C (dec.) (lit.)

solubilidade

water: soluble 0.4 g/L at 20 °C

traços de cátion

Ca: ≤0.001%
Fe: ≤0.005%
Mg: ≤5 ppm
heavy metals (as Pb): ≤0.001%

SMILES string

OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O

InChI

1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)

InChI key

KCXVZYZYPLLWCC-UHFFFAOYSA-N

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Descrição geral

Ethylenediaminetetraacetic acid (EDTA) is a hydrophilic metal chelating agent that transforms metal ions into inactive, cyclic metal complexes. Hence, it has industrial application for resolving metal contamination.

Aplicação

Ethylenediaminetetraacetic acid has been used:
  • as a component of labeling buffer, which is used in the washing step during cell fractionation{155)
  • for investigating the effect of papain enzyme on wound debridement and other skin issues
  • for harvesting rat arterial smooth muscle cell after its pre-treatment for its use in flow cytometry analysis

Embalagem

1 kg in poly bottle
100, 500 g in poly bottle

Ações bioquímicas/fisiológicas

Ethylenediaminetetraacetic acid (EDTA) is not easily administered by the gastrointestinal tract. Intravenous administration of sodium EDTA results in hypocalcemic tetany. It is generally useful in plasma or molecular diagnostics and acts by chelating calcium. EDTA serves as an anticoagulant for haematological cell counting and cell morphological analysis.

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Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

hazcat

Eye Irrit. 2

storage_class_code

11 - Combustible Solids

WGK Alemanha

WGK 2

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Certificado de análise

Certificado de origem

CRC Desk Reference of Clinical Pharmacology, 215-215 (1997)
Henry's Clinical Diagnosis and Management by Laboratory Methods E-book, 28-28 (2011)
Streaming of proteolytic enzyme solutions for wound debridement: a feasibility study
Yaakobi T, et al.
Wounds : a compendium of clinical research and practice, 16, 201-205 (2004)
Adsorption of metal-ethylenediaminetetraacetic acid chelates onto lake sediment
Sillanpaa M and Ramo J
Chemosphere, 45, 881-885 (2001)
Renée S Suen et al.
The American journal of pathology, 179(3), 1549-1559 (2011-07-02)
Because both endothelin-1 (ET-1) and angiotensin II (AngII) are independent mediators of arterial remodeling, we sought to determine the role of ET receptor inhibition in AngII-accelerated atherosclerosis and aortic aneurysm formation. We administered saline or AngII and/or bosentan, an endothelin...
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