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ED

Sigma-Aldrich

Ethylenediaminetetraacetic acid

purified grade, ≥98.5%, powder

Sinônimo(s):
Edathamil, (Ethylenedinitrilo)tetraacetic acid, EDTA, Ethylenedinitrilotetraacetic acid
Fórmula linear:
(HO2CCH2)2NCH2CH2N(CH2CO2H)2
Número CAS:
Peso molecular:
292.24
Beilstein:
1716295
Número EC:
Número MDL:
eCl@ss:
39030907
ID de substância PubChem:

Nível de qualidade

200

grau

purified grade

teor

≥98.5%

forma

powder

pf

250 °C (dec.) (lit.)

solubilidade

water: soluble 0.4 g/L at 20 °C

SMILES string

OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O

InChI

1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)

InChI key

KCXVZYZYPLLWCC-UHFFFAOYSA-N

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Descrição geral

Ethylenediaminetetraacetic acid (EDTA) is an affordable chelating agent. It is an aminopolycarboxylic acid and a hexadentate ligand and forms octahedral complex with cations. Ethylenediaminetetraacetic acid (EDTA) is not recommended for phytoremediation as it can leach into natural water resources. It is used in cosmetics and pharmaceutical industry. It triggers platelet aggregation in pseudothrombocytopenia. In chelation therapy, it elicits protection from oxidative damage during blood and lipid peroxidation and may be useful to treat cardiovascular and carbon tetrachloride induced liver fibrosis.

Aplicação

Ethylenediaminetetraacetic acid may be used:
  • as a component of staining buffer
  • as buffer component for incubating epithelial cell adhesion molecule (EpCAM+) cells with fluorescein isothiocyanate (FITC)-conjugated antibody for cell sorting studies
  • for treating epithelial cells for isolation of mucosal myofibroblasts

Embalagem

1 kg in poly bottle
100, 500 g in poly bottle
5 kg in poly drum

Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Declarações de precaução

Classificações de perigo

Eye Irrit. 2

Código de classe de armazenamento

13 - Non Combustible Solids

WGK

WGK 2

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Certificado de análise

Certificado de origem

Functional modulation of Crohn?s disease myofibroblasts by anti-tumor necrosis factor antibodies
Di Sabatino A, et al.
Gastroenterology, 133(1), 137-149 (2007)
Induced Plant Accumulation of Lithium
Kavanagh L, et al.
Geostandards Newsletter, 8(2), 56-56 (2018)
Membrane glucocorticoid receptors (mGCR) are expressed in normal human peripheral blood mononuclear cells and up-regulated after in vitro stimulation and in patients with rheumatoid arthritis
Bartholome B, et al.
Faseb Journal, 18(1), 70-80 (2004)
Ethylenediaminetetraacetic acid induces antioxidant and anti-inflammatory activities in experimental liver fibrosis
Gonzalez-Cuevas J, et al.
Redox Report, 16(2), 62-70 (2011)
The phenotypes of pluripotent human hepatic progenitors
Schmelzer E, et al.
Stem Cells, 24(8), 1852-1858 (2006)

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