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Documentos Principais

I1892

Supelco

Ibuprofen sodium salt

≥98% (GC)

Sinônimo(s):

α-Methyl-4-(isobutyl)phenylacetic acid

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100 G
R$ 1.442,00
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Disponível para enviar em20 de maio de 2025Detalhes


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100 G
R$ 1.442,00
500 G
R$ 5.184,00

About This Item

Fórmula linear:
C13H17O2Na
Número CAS:
Peso molecular:
228.26
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24

R$ 1.442,00


Disponível para enviar em20 de maio de 2025Detalhes


Request a Bulk Order

grau

analytical standard

Nível de qualidade

Ensaio

≥98% (GC)

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

solubilidade

H2O: 100 mg/mL, clear to slightly hazy

aplicação(ões)

forensics and toxicology
pharmaceutical (small molecule)

Formato

neat

cadeia de caracteres SMILES

[Na+].CC(C)Cc1ccc(cc1)C(C)C([O-])=O

InChI

1S/C13H18O2.Na/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15;/h4-7,9-10H,8H2,1-3H3,(H,14,15);/q;+1/p-1

chave InChI

PTTPUWGBPLLBKW-UHFFFAOYSA-M

Informações sobre genes

Descrição geral

Ibuprofen belongs to the class of non-steroidal anti-inflammatory drugs,[1] widely used for the treatment of mild to moderate pain and several forms of arthritis.[2]

Aplicação

Ibuprofen sodium salt may be used as a model drug to study the intercalation mechanism via ion exchange reaction between ibuprofen and a biocompatible hydrotalcite compound.[3]
Ibuprofen sodium salt may be used as an analytical reference standard for the qualification of the analyte in wastewaters using high-performance liquid chromatography (HPLC).[1]
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Ações bioquímicas/fisiológicas

Cyclooxygenase (COX) inhibitor that has greater activity against COX-1 than against COX-2.

Produtos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


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Certificados de análise (COA)

Lot/Batch Number

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Sigma-Aldrich

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Supelco

PHR1435

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Emanuele Mauri et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 146, 143-149 (2019-11-15)
Ibuprofen (IBU) is a non-steroidal anti-inflammatory drug (NSAID) commonly used in the treatment of pain, fever and inflammation. However, the administration of IBU in its free carboxylic acid form is strongly dependent on its limited solubility in aqueous solution. This
Determination of non-steroidal anti-inflammatory drugs in wastewaters by magnetic matrix solid phase dispersion?HPLC
Aguilar-Arteaga.K, et al.
Talanta, 80(3), 1152-1157 (2010)
Intercalation compounds of hydrotalcite-like anionic clays with antiinflammatory agents?I. Intercalation and in vitro release of ibuprofen
Ambrogi V, et al.
International Journal of Pharma Research & Review, 220, 23-32 (2001)
Fareeha Batool et al.
Materials (Basel, Switzerland), 11(4) (2018-04-13)
Ibuprofen (IBU) has been shown to improve periodontal treatment outcomes. The aim of this study was to develop a new anti-inflammatory scaffold by functionalizing an electrospun nanofibrous poly-ε-caprolactone membrane with IBU (IBU-PCL) and to evaluate its impact on periodontal inflammation
Abegaz Tizazu Andrgie et al.
Polymers, 12(11) (2020-11-12)
Hydrogels have been investigated as ideal biomaterials for wound treatment owing to their ability to form a highly moist environment which accelerates cell migration and tissue regeneration for prompt wound healing. They can also be used as a drug carrier

Questions

1–3 of 3 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  3. Can you please confirm if your product Ibuprofen sodium salt (Product No. (I1892); CAS 31121-93-4) is the standard dihydrate form?

    1 answer
    1. The product has a water specification of less than or equal to 15% which is reported on the lot-specific Certificate of Analysis. If a lot is 13.5% water by mass, this equates to 1.98 moles of water. and could be considered approximately dihydrate. The specification allows for lots with lesser water content, but historically, most or all lots fall between 12.5 and 14.5% water, indicating the dihydrate form.

      Helpful?

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