M0200000

Mannitol

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):
Mannite, D-Mannitol
Empirical Formula (Hill Notation):
C6H14O6
Número CAS:
Peso molecular:
182.17
Beilstein/REAXYS Number:
1721898
Número MDL:
ID de substância PubChem:
NACRES:
NA.24

grau

pharmaceutical primary standard

forma

neat

manufacturer/tradename

EDQM

pf

167-170 °C (lit.)

Setor em destaque

Pharmaceutical (small molecule)

formato

neat

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1

InChI key

FBPFZTCFMRRESA-KVTDHHQDSA-N

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Ações bioquímicas/fisiológicas

A sugar alcohol sweet tastant. Used in sweetness inhibition studies.

Embalagem

Unit quantity: 1200 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Atenção

Outras notas

Sales restrictions may apply.

storage_class_code

11 - Combustible Solids

WGK Alemanha

WGK 2

Certificado de análise

Certificado de origem

Heikki O Koskela et al.
Chest, 124(6), 2171-2177 (2003-12-11)
To compare a new bronchial provocation test, the mannitol challenge, with cold air and histamine challenges to demonstrate airway hyperresponsiveness (AHR) in patients with difficult-to-diagnose asthma. A prospective study. Thirty-seven consecutive patients with recently diagnosed, steroid-naive, mild, or atypical asthma...
Diana Bilton et al.
Thorax, 69(12), 1073-1079 (2014-09-24)
Bronchiectasis is characterised by excessive production of mucus and pulmonary exacerbations. Inhaled osmotic agents may enhance mucociliary clearance, but few long-term clinical trials have been conducted. To determine the impact of inhaled mannitol on exacerbation rates in patients with non-cystic...
Heikki O Koskela et al.
Chest, 125(6), 1985-1992 (2004-06-11)
To define whether coughing during mannitol challenge is a nonspecific side effect of this challenge or is associated with asthma. A prospective study. University hospital. Thirty-seven steroid-naive, asthmatic subjects and 10 healthy subjects. The participants completed a symptom questionnaire, recorded...
Heikki O Koskela et al.
Chest, 124(4), 1341-1349 (2003-10-14)
To compare the sensitivity and validity of mannitol, histamine, and cold air challenges to demonstrate the effect of inhaled corticosteroids (ICS) in asthma. A prospective study. Seventeen patients with recently diagnosed, steroid-naive asthma who fulfilled the diagnostic criteria of Finnish...
Traumatic intracranial hypertension.
Nino Stocchetti et al.
The New England journal of medicine, 370(22), 2121-2130 (2014-05-30)

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