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Merck

P1754

Sigma-Aldrich

TWEEN® 80

viscous liquid

TWEEN® 80

Sinônimo(s):

TWEEN® 80, Mono-oleato de POE (20) sorbitano, Mono-oleato de polietilenoglicol sorbitano, Mono-oleato de polioxietileno sorbitano, Polissorbato 80

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25 ML
R$ 195,00
500 ML
R$ 507,00
1 L
R$ 721,00
1 GAL
R$ 1.318,00

R$ 195,00

Disponível para enviar em10 de novembro de 2025Detalhes

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Sobre este item

Número CAS:
9005-65-6
Número MDL:
MFCD00082107
Código UNSPSC:
12161900
NACRES:
NA.21

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fonte biológica

Porcine (tallow)
bovine (tallow)

Nível de qualidade

200

descrição

non-ionic

Formulário

viscous liquid

peso molecular

micellar avg mol wt 79,000
average mol wt 1310

composição

Oleic acid, ≥58.0% (balance primarily linoleic, palmitic, and stearic acids)

número de agregação

60

CMC

0.012 mM (20-25°C)

viscosidade

400-620 mPa.s

temperatura de transição

cloud point 65 °C

solubilidade

water: soluble, clear to slightly hazy, colorless to yellow

densidade

1.064 g/cm3

HLB

15

aplicação(ões)

cell analysis

cadeia de caracteres SMILES

CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(CC(O1)OCCO)OCCO)OCCO

InChI

1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-27-29(39-22-19-34)32-28(38-21-18-33)26-31(42-32)41-23-20-35/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+

chave InChI

RGPBUVUVZKQNHD-MDZDMXLPSA-N

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1 of 4

Este Item
P8074P4780STS0204
TWEEN® 80 viscous liquid

Sigma-Aldrich

P1754

TWEEN® 80

TWEEN® 80 BioXtra, viscous liquid

Sigma-Aldrich

P8074

TWEEN® 80

TWEEN® 80 suitable for cell culture, suitable for insect cell culture, viscous liquid

Sigma-Aldrich

P4780

TWEEN® 80

TWEEN® 80 viscous liquid

Sigma-Aldrich

STS0204

TWEEN® 80

form

viscous liquid

form

viscous liquid

form

viscous liquid

form

viscous liquid

aggregation number

60

aggregation number

60

aggregation number

-

aggregation number

-

application(s)

cell analysis

application(s)

-

application(s)

-

application(s)

-

biological source

Porcine (tallow), bovine (tallow)

biological source

-

biological source

-

biological source

-

viscosity

400-620 mPa.s

viscosity

-

viscosity

-

viscosity

300—500 cP(25 °C)

density

1.064 g/cm3

density

1.06 g/mL at 25 °C

density

1.06 g/mL at 25 °C (lit.), 1.07 g/cm3 at 25 °C (lit.)

density

1.064 g/cm3

Descrição geral

Tween® 80 é um detergente não iônico e surfactante, classificado como éster de sorbitano e ácido oleico. É um composto versátil comumente empregado em várias aplicações biológicas, incluindo lise celular, isolamento de núcleos e fracionamento celular. Além disso, o Tween 80 é utilizado na estabilização de proteínas e na facilitação de estudos de membrana proteica. Sua eficácia se deve ao fato de pertencer ao grupo dos polissorbatos, caracterizado pela combinação de ésteres oleicos de sorbitol e sorbitano com cadeias de polietilenoglicol. Esses recursos estruturais contribuem para os recursos emulsificantes do Tween 80 e uma ampla variedade de aplicações.

Aplicação

Detergente não iônico usado para extração seletiva de proteínas e isolamento de núcleos de linhagens de células de mamíferos.
O TWEEN® 80 foi usado em solução veículo de medicamentos para injeções específicas em camundongos e ratos.[1][2] Ele foi usado para a determinação da atividade da estearase em células bacterianas.[3]

Ações bioquímicas/fisiológicas

O TWEEN® 80 é um tensoativo de polissorbato que ajuda a estabilizar proteínas e em estudos de membranas proteicas. Ele é regulamente usado para a extração de proteínas de membrana e isolamento de núcleos celulares.[4][5][6]

Características e benefícios

  • Excelente agente umectante e dispersante
  • Surfactante altamente versátil para suas pesquisas em biologia celular e bioquímica

Outras notas

Para mais informações sobre nossa linha de Bioquímicos, preencha este formulário.

Informações legais

TWEEN is a registered trademark of Croda International PLC

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

>235.4 °F - closed cup

Ponto de fulgor (°C)

> 113 °C - closed cup

Equipamento de proteção individual

Eyeshields, Gloves

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
BCCN6549
BCCN4705
BCCM9515
BCCM7843
BCCM6321

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Questions

1–10 of 11 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. This material is free of residual solvents?

    1 answer

    1. This product is not tested for residual solvents. Should this be a requirement, see product 817061, which is tested for Ethylene Oxide, 1,4-Dioxane, and Ethylene glycol. Please see the link below to review this item:
      https://www.sigmaaldrich.com/product/mm/817061

      Helpful?

  4. What is the boiling point of this specific Tween 80 product?

    1 answer

    1. This product is not tested for boiling point. However, various reference sources cite a boiling point of approximately 100°C.

      Helpful?

  5. Hello, Is there an expiration date or retest date for this product?

    1 answer

    1. This product is not assigned an expiration date. It is assigned a recommended retest date of approximately 4 years after the quality release date. A recommended retest date is the time during which the product is expected to remain within established stability specifications, provided that it has been stored under defined conditions. After the Retest Date, product samples should be examined to ensure that the product is still in compliance with the established specifications.

      For more information, you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/US/en/life-science/quality-and-regulatory-management/quality-services.

      Helpful?

  6. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  7. Is it normal for the color of Product P1754, TWEEN® 80, to change from lot to lot?

    1 answer

    1. Yes. According to Sigma-Aldrich's specifications, Product No. P1754 can appear bright yellow to yellow with a green cast.  Please see our Specification Sheet for more information.

      Helpful?

  8. Is Product P1754, TWEEN® 80, sterile?

    1 answer

    1. The product is not sterile. Autoclaving a solution of TWEEN 80 is generally not advised. Sterile filtration is more easily done if the liquid is warmed to about 40°C and alternate portions of hot distilled water and TWEEN 80 are poured through the 0.22 μm filter. The TWEEN 80 will blend and remain in solution.

      Helpful?

  9. Is Product P1754, TWEEN® 80, tested for RNase and DNase activity?

    1 answer

    1. No. Product P1754 is not tested for contaminating RNase and DNase activity.  Product P5188 is a Molecular Biology grade product that has been tested for DNase and RNase.

      Helpful?

  10. Is Product P1754, TWEEN® 80, cell culture tested?

    1 answer

    1. No, P1754 is not cell culture tested, but product P4780 is cell culture tested TWEEN 80.

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1–10 of 11 Questions  
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