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PHR1000

Supelco

Dextrose

Pharmaceutical Secondary Standard; Certified Reference Material

Sinônimo(s):
D-(+)-Glucose, Dextrose
Empirical Formula (Hill Notation):
C6H12O6
Número CAS:
Peso molecular:
180.16
Beilstein:
1724615
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.24

Nível de qualidade

300

grau

certified reference material
pharmaceutical secondary standard

teor

99.9%

Certificado de análise (CofA)

current certificate can be downloaded

analyte chemical class(es)

oligosaccharides

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

pf

150-152 °C (lit.)

application(s)

detection
food and beverages
pharmaceutical (small molecule)

formato

neat

rastreabilidade da farmacopeia

traceable to PhEur Y0001745
traceable to USP 1181302

temperatura de armazenamento

2-30°C

SMILES string

OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1

InChI key

WQZGKKKJIJFFOK-DVKNGEFBSA-N

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Descrição geral

Dextrose belongs to the class of sugars, and is a preferred source of carbohydrate in parenteral nutrition regimens. It is widely used in solutions to adjust tonicity, as a sweetening agent, wet granulation diluent/binder, direct-compression tablet diluent/binder, etc. It is considered only for short term clinical use, since it is deficient in electrolytes.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicação

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. Dextrose has been used as a standard in the determination of additives like glucose in beverages using high performance liquid chromatography (HPLC). It may also be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using spectrophotometric technique.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAB7785 in the slot below. This is an example certificate only and may not be the lot that you receive.

Código de classe de armazenamento

11 - Combustible Solids

WGK

WGK 1

Certificado de análise

Certificado de origem

Handbook of Starch Hydrolysis Products and their Derivatives (1995)
Determination of Additives in Beverages Using Ascentis Express Columns
Shimelis O, et al.
Sigma data, 30 (2013)
A multicommuted flow system for the determination of dextrose in parenteral and hemodialysis concentrate solutions
Knochen M, et al. et al.
Journal of Pharmaceutical and Biomedical Analysis, 37(4), 823-828 (2005)
Handbook of Pharmaceutical Excipients (1986)
Saunders Handbook of Veterinary Drugs - E-Book: Small and Large Animal (2010)

Artigos

HPLC Analysis of Sugars by HILIC Chromatography using Ascentis® Express OH-5 Column with ELSD Detection

Separation of Dextrose, Pharmaceutical Secondary Standard; Certified Reference Material; Sucrose; Maltitol, Pharmaceutical Secondary Standard; Certified Reference Material

Protocolos

Determination of Additives in Beverages Using Ascentis® Express Columns

RP-Amide and HILIC, both amenable to the analysis of polar compounds, were successfully used to resolve several beverage components, including sugars, vitamins, sweeteners, preservatives, and caffeine.

HPLC Analysis of Sugars on SUPELCOSIL™ LC-NH2

A protocol discussing HPLC Analysis of Sugars on SUPELCOSIL™ LC-NH2

Conteúdo relacionado

HPLC Analysis of Sugars on SUPELCOSIL™ LC-NH2

HPLC Analysis of Sugars on SUPELCOSIL™ LC-NH2

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