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PHR1007

Supelco

Mannitol

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):
D-Mannitol, Mannite
Empirical Formula (Hill Notation):
C6H14O6
CAS Number:
Molecular Weight:
182.17
Beilstein:
1721898
Número EC:
Número MDL:
ID de substância PubChem:
Número E:
E421
NACRES:
NA.24

grau

certified reference material
pharmaceutical secondary standard

Nível de qualidade

300

Agency

traceable to Ph. Eur. M0200000
traceable to USP 1375105

Certificado de análise (CofA)

current certificate can be downloaded

analyte chemical class(es)

oligosaccharides

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

pf

167-170 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

2-30°C

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1

InChI key

FBPFZTCFMRRESA-KVTDHHQDSA-N

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Descrição geral

Mannitol is an osmotic diuretic with a variety of clinical applications,[1] one of which is the reduction of intracranial pressure. It is also found to be protective against ischemic and nephrotoxic acute renal failure.[2]
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicação

Mannitol may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using capillary isotachophoresis technique.[3]
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Ações bioquímicas/fisiológicas

A sugar alcohol sweet tastant. Used in sweetness inhibition studies.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Ion Mobility: TWCCSN2 value of 132.3 Å2 [M-H]-

The collision cross section (CCS) measurement was provided by Waters Corporation, using the SYNAPT XS mass spectrometer.
For a description and overview of how ion mobility enables the measurement of the CCS of an ion visit ims.waters.com.
Further information on the SYNAPT XS mass spectrometer can be found on the IMS microsite and product webpage.

TWCCS measurements are expected to be within 2% of this reference value.

P/N PHR1007 is part of the Waters Extractables & Leachables UNIFI scientific library which can be downloaded from Waters Marketplace.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAB7668 in the slot below. This is an example certificate only and may not be the lot that you receive.

Código de classe de armazenamento

11 - Combustible Solids

WGK

WGK 1

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

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