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PHR1048

Supelco

4-Hydroxybenzoic acid

Pharmaceutical Secondary Standard; Certified Reference Material

Fórmula linear:
HOC6H4CO2H
Número CAS:
Peso molecular:
138.12
Beilstein:
970950
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.24

Nível de qualidade

300

grau

certified reference material
pharmaceutical secondary standard

Certificado de análise (CofA)

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

pf

213-217 °C (lit.)

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)

formato

neat

rastreabilidade da farmacopeia

traceable to USP 1609013

temperatura de armazenamento

2-30°C

SMILES string

OC(=O)c1ccc(O)cc1

InChI

1S/C7H6O3/c8-6-3-1-5(2-4-6)7(9)10/h1-4,8H,(H,9,10)

InChI key

FJKROLUGYXJWQN-UHFFFAOYSA-N

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Descrição geral

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. 4-Hydroxybenzoic acid belongs to the class of aromatic acids, which may be used as a preservative in cosmetics, pharmaceuticals and as a synthetic flavoring agent in food products.

Aplicação

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAB2176 in the slot below. This is an example certificate only and may not be the lot that you receive.

Pictogramas

CorrosionExclamation mark

Palavra indicadora

Danger

Frases de perigo

Classificações de perigo

Eye Dam. 1 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

WGK

WGK 1

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Certificado de análise

Certificado de origem

Handbook of Preservatives (2004)
M G Soni et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 39(6), 513-532 (2001-05-11)
Propyl paraben (CAS no. 94-13-3) is a stable, non-volatile compound used as an antimicrobial preservative in foods, drugs and cosmetics for over 50 years. It is an ester of p-hydroxybenzoate. Propyl paraben is readily absorbed via the gastrointestinal tract and
L C Goudas et al.
Anesthesia and analgesia, 89(5), 1209-1215 (1999-11-30)
Intracerebroventricular (ICV) morphine administration is effective for the management of refractory cancer pain. Recent preclinical observations of acute depletion of the major endogenous intracellular antioxidant glutathione (GSH) in brain and peripheral organs after ICV morphine in rodents led us to
Letian X Xie et al.
The Journal of biological chemistry, 287(28), 23571-23581 (2012-05-18)
Most of the Coq proteins involved in coenzyme Q (ubiquinone or Q) biosynthesis are interdependent within a multiprotein complex in the yeast Saccharomyces cerevisiae. Lack of only one Coq polypeptide, as in Δcoq strains, results in the degradation of several
Suri Roowi et al.
Molecular nutrition & food research, 53 Suppl 1, S68-S75 (2009-05-06)
Human urine was collected over a 24 h period after the consumption of 250 mL of (i) water, (ii) orange juice, and (iii) orange juice plus 150 mL of full fat natural yoghurt. The orange juice contained 168 micromol of

Protocolos

HPLC Analysis of Benzoic Acid and Related Compounds on Ascentis® RP-Amide

Separation of 4-Hydroxybenzoic acid; Acetylsalicylic acid; Benzoic acid; Salicylic acid; Ethyl 4-hydroxybenzoate

HPLC Analysis of Benzoic Acid Derivatives on Ascentis® C18

HPLC Analysis of Benzoic Acid Derivatives on Ascentis® C18

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