Pharmaceutical Secondary Standard; Certified Reference Material

2,2′-Iminodiethanol, Bis(2-hydroxyethyl)amine
Fórmula linear:
Número CAS:
Peso molecular:
Beilstein/REAXYS Number:
Número EC:
Número MDL:
ID de substância PubChem:

Nível de qualidade



certified reference material
pharmaceutical secondary standard

densidade de vapor

3.6 (vs air)

pressão de vapor

<0.98 atm ( 100 °C)



Certificado de análise (CofA)

current certificate can be downloaded

temperatura de autoignição

689 °F

Lim. expl.

10.6 %


HPLC: suitable
gas chromatography (GC): suitable

índice de refração

n20/D 1.477 (lit.)


217 °C/150 mmHg (lit.)


28 °C (lit.)


1.097 g/mL at 25 °C (lit.)

Setor em destaque

Pharmaceutical (small molecule)



rastreabilidade da farmacopeia

traceable to USP 1192808

SMILES string




InChI key


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Descrição geral

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Diethanolamine is commonly used as a chemical intermediate and as a surface-active agent in agricultural products, pharmaceutical formulations and cosmetics.


These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAC3260 in the slot below. This is an example certificate only and may not be the lot that you receive.

Palavra indicadora



Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2 - STOT RE 2 Oral


10 - Combustible liquids

WGK Alemanha


Ponto de fulgor (ºF)

280.4 °F - closed cup

Ponto de fulgor (ºC)

138 °C - closed cup

Certificado de análise

Certificado de origem

Ecotoxicological evaluation of diethanolamine using a battery of microbiotests
Zurita LJ, et al.
Toxicology in vitro, 19(7), 879-886 (2005)
Ken-Ichi Kusumoto et al.
Journal of biomedical materials research. Part A, 91(1), 1-10 (2008-08-07)
Understanding of lipidic materials used for gene delivery system is essential for the effective design and development of potential applications in basic and therapeutic research. This study aimed to evaluate the biological activity of totally synthesized ditetradecylacetyldiethanolaminetrimethylammonium (TMA-C2-DEA-C14) as gene...
Shiguo Sun et al.
Dalton transactions (Cambridge, England : 2003), (38)(38), 7969-7974 (2009-09-23)
A series of ruthenium(II) tris-bipyridyl complexes covalently linked with different amine reductants such as tripropylamine (TPrA), ethanolamine and diethanolamine for an electrochemiluminescence (ECL) system have been synthesized. Their ECL property at different working electrodes has been studied with and without...
William Conway et al.
Environmental science & technology, 46(13), 7422-7429 (2012-05-25)
The kinetics of the fast reversible carbamate formation reaction of CO(2)(aq) with a series of substituted cyclic secondary amines as well as the noncyclic secondary amine diethanolamine (DEA) has been investigated using the stopped-flow spectrophotometric technique at 25.0 °C. The...
S H Zeisel et al.
The Biochemical journal, 232(2), 403-408 (1985-12-01)
An understanding of the biosynthesis and metabolism of dimethylamine (DMA) is important because it is a precursor of dimethylnitrosamine (nitroso-DMA). DMA is the major short-chain aliphatic amine in human and rat urine. DMA is formed from trimethylamine (TMA), which, in...

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