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PHR1416

Supelco

Sodium Citrate

Pharmaceutical Secondary Standard; Certified Reference Material

Sinônimo(s):
Trisodium citrate dihydrate, Citric acid trisodium salt dihydrate, Sodium citrate tribasic dihydrate
Fórmula linear:
HOC(COONa)(CH2COONa)2 · 2H2O
Número CAS:
Peso molecular:
294.10
Beilstein:
6104939
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.24

Nível de qualidade

300

grau

certified reference material
pharmaceutical secondary standard

Agency

traceable to USP 1613859

Certificado de análise (CofA)

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

pf

>300 °C (lit.)

application(s)

pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

2-30°C

SMILES string

O.O.[Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O

InChI

1S/C6H8O7.3Na.2H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;2*1H2/q;3*+1;;/p-3

InChI key

NLJMYIDDQXHKNR-UHFFFAOYSA-K

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Descrição geral

Sodium citrate, also known as E331, is a tri-sodium salt of citric acid. In food products, it is commonly used as a flavor and preservative. In pharmaceutical formulations, it is used as a buffer, emulsifier and sequestering agent.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicação

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Sodium citrate may be used as a pharmaceutical reference standard for the determination of the analyte in raw material, food and pharmaceutical formulations by titrimetry.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAC3037 in the slot below. This is an example certificate only and may not be the lot that you receive.

Código de classe de armazenamento

13 - Non Combustible Solids

WGK

WGK 1

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Certificado de análise

Insira o número de lote para pesquisar o Certificado de análise (COA).

Certificado de origem

Insira o número de lote para pesquisar o Certificado de origem (COO).

Mais documentos

Quotes and Ordering

Sodium citrate
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 3574-3574 (2017)
Sodium citrate
Handbook of Pharmaceutical Excipients 6th edition Pharmaceutical Press, 640-642 (2009)
Sodium citrate
Pharmacopeia, US
United States Pharmacopeia/National Formulary, 4069-4069 (2018)
Sara Svensson et al.
International journal of nanomedicine, 9, 775-794 (2014-02-20)
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Y V Sanders et al.
Journal of thrombosis and haemostasis : JTH, 12(7), 1066-1075 (2014-04-23)
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