PHR1557

Methylene Chloride

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): Dichloromethane, Methylene chloride
• Empirical Formula (Hill Notation): CH₂Cl₂
• CAS Number: 75-09-2
• Molecular Weight: 84.93
• Beilstein: 1730800
• Número EC: 200-838-9
• Número MDL: MFCD00000881
• ID de substância PubChem: 329823466
• NACRES: NA.24

Properties

• grau: certified reference material; pharmaceutical secondary standard
• Nível de qualidade: 300
• Agency: traceable to USP 1601441
• densidade de vapor: 2.9 (vs air)
• pressão de vapor: 24.45 psi ( 55 °C); 6.83 psi ( 20 °C)
• Certificado de análise (CofA): current certificate can be downloaded
• temperatura de autoignição: 1223 °F
• Lim. expl.: 22 %
• embalagem: ampule of 3x1.2 mL each
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• índice de refração: n20/D 1.424 (lit.)
• pb: 39.8-40 °C (lit.)
• pf: −97 °C (lit.)
• densidade: 1.325 g/mL at 25 °C (lit.)
• application(s): pharmaceutical (small molecule)
• formato: neat
• temperatura de armazenamento: 2-30°C
• SMILES string: ClCCl
• InChI: 1S/CH2Cl2/c2-1-3/h1H2
• InChI key: YMWUJEATGCHHMB-UHFFFAOYSA-N

Description

Descrição geral

Methylene chloride, also known as dichloromethane, is an organic solvent with widespread industrial applications.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicação

Methylene Chloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by gas chromatography (GC) technique.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAB7796 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety Information

• Pictogramas: GHS07,GHS08
• Palavra indicadora: Warning
• Frases de perigo: H315 - H319 - H336 - H351
• Declarações de precaução: P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Classificações de perigo: Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órgãos-alvo: Central nervous system
• Código de classe de armazenamento: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Ponto de fulgor (ºF): Not applicable
• Ponto de fulgor (ºC): Not applicable