Merck
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PHR1758

Supelco

Thiourea

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):
Thiourea, Thiocarbamide, Sulfourea
Linear Formula:
NH2CSNH2
CAS Number:
Molecular Weight:
76.12
Beilstein:
605327
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.24

Nível de qualidade

300

grau

certified reference material
pharmaceutical secondary standard

Certificado de análise (CofA)

current certificate can be downloaded

embalagem

pkg of 200 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

pf

170-176 °C (lit.)

application(s)

pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

2-30°C

SMILES string

NC(N)=S

InChI

1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)

InChI key

UMGDCJDMYOKAJW-UHFFFAOYSA-N

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Descrição geral

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Thiourea is a chaotropic agent or strong denaturant. It has been used to solubilize membrane and organelle specific proteins for analysis by two-dimensional gel electrophoresis. Thiourea is a free radical scavenger of the peroxide radical. It was shown to inhibit lipid peroxidation and UV-induced crosslinking of collagen. As a chelator of cuprous copper, thiourea inhibits this intermediate in oxidative reactions of cupric ion. This process afforded protection of bovine albumin from copper-mediated oxidative reactions.

Aplicação

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Chaotropic agent; strong denaturant. Increases solubility and recovery of proteins

Nota de análise

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAA8226 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Palavra indicadora

Warning

Classificações de perigo

Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Repr. 2

Código de classe de armazenamento

11 - Combustible Solids

WGK

WGK 3

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

More Documents

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