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30089

Sigma-Aldrich

L-Cysteine

BioUltra, ≥98.5% (RT)

Sinônimo(s):
(R)-2-Amino-3-mercaptopropionic acid
Fórmula linear:
HSCH2CH(NH2)CO2H
Número CAS:
Peso molecular:
121.16
Beilstein:
1721408
Número EC:
Número MDL:
eCl@ss:
32160406
ID de substância PubChem:
NACRES:
NA.26

linha de produto

BioUltra

Nível de qualidade

200

teor

≥98.5% (RT)

forma

powder or crystals

atividade óptica

[α]20/D +8.0±0.5°, c = 5% in 5 M HCl

technique(s)

HPLC: suitable

Impurezas

insoluble matter, passes filter test
≤0.5% foreign amino acids

resíduo de ignição

≤0.05% (as SO4)

perda

≤0.05% loss on drying, 20 °C (HV)

cor

white

pf

240 °C (dec.) (lit.)

solubilidade

1 M HCl: 1 M at 20 °C, clear, colorless

traços de ânion

chloride (Cl-): ≤100 mg/kg
sulfate (SO42-): ≤50 mg/kg

traços de cátion

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
NH4+: ≤500 mg/kg
Na: ≤100 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

1 M in 1 M HCl

Absorção UV

λ: 260 nm Amax: 1.5
λ: 280 nm Amax: 0.2

SMILES string

N[C@@H](CS)C(O)=O

InChI

1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1

InChI key

XUJNEKJLAYXESH-REOHCLBHSA-N

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Categorias relacionadas

Aplicação

L-Cysteine has been used in quenching of unreacted maleimide during antibody grafting. It has also been used in the preparation of nitrosocysteine stock solution, that has been employed to induce S-nitrosylation to achieve reversible cysteine modification.

Ações bioquímicas/fisiológicas

Cysteine is one of the functional amino acids that regulates metabolism for growth, reproduction, maintenance and immunity. Cysteine provides the disulfide linkage in proteins. It is directly associated with the transport of sulfur. Taurine, a metabolic product of cysteine acts as an antioxidant and controls the cellular redox state. Cysteine is involved in the formation of hydrogen sulfide that is utilized as a signaling molecule.
NMDA glutamatergic receptor agonist.

Código de classe de armazenamento

13 - Non Combustible Solids

WGK

WGK 1

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Certificado de análise

Certificado de origem

Preparation of polyion complex micelles from poly(ethylene glycol)-block-polyions
Nuria Bayo-Puxan
Journal of Controlled Release : Official Journal of the Controlled Release Society, 156(2), 118-127 (2011)
Resin-assisted enrichment of thiols as a general strategy for proteomic profiling of cysteine-based reversible modifications
Jia Guo
Nature Protocols, 9(1), 64-75 (2014)
Amino acids: metabolism, functions, and nutrition
Guoyao Wu
Amino Acids, 37(1), 1-17 (2009)
Takeshi Annoura et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(5), 2158-2170 (2014-02-11)
The 10 Plasmodium 6-Cys proteins have critical roles throughout parasite development and are targets for antimalaria vaccination strategies. We analyzed the conserved 6-cysteine domain of this family and show that only the last 4 positionally conserved cysteine residues are diagnostic
Eun Young Park et al.
Journal of agricultural and food chemistry, 62(26), 6183-6189 (2014-06-01)
The present study examined the impact of the supplementation of glutathione (GSH), γ-L-glutamyl-L-cysteinyl-glycine, on human blood GSH levels. Healthy human volunteers were orally supplemented with GSH (50 mg/kg body weight). Venous blood was collected from the cubital vein before and

Artigos

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

Protocolos

GC Analysis of Amino Acids (as TBDMS Derivatives) on SLB®-5ms (20 m x 0.18 mm I.D., 0.18 μm), Fast GC Analysis

Separation of L-Alanine; Glycine; L-Valine; L-Leucine; L-Isoleucine; L-Proline; L-Methionine; L-Serine; L-Threonine; L-Phenylalanine; L-Aspartic acid; L-4-Hydroxyproline; L-Cysteine; L-Glutamic acid; L-Asparagine; L-Lysine; L-Glutamine; L-Histidine; L-Tyrosine; L-Tryptophan; L-Cystine

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