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41639

Sigma-Aldrich

Dimetilsulfóxido

BioUltra, ≥99.5% (GC)

Sinônimo(s):

DMSO

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About This Item

Fórmula linear:
(CH3)2SO
Número CAS:
67-68-5
Peso molecular:
78.13
Beilstein:
506008
Número CE:
200-664-3
Número MDL:
MFCD00002089
Código UNSPSC:
12191502
ID de substância PubChem:
57650076
NACRES:
NA.25

R$ 1.077,00

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grau

Molecular Biology

Nível de qualidade

200

densidade de vapor

2.7 (vs air)

pressão de vapor

0.42 mmHg ( 20 °C)

linha de produto

BioUltra

Ensaio

≥99.5% (GC)

Formulário

liquid

temperatura de autoignição

573 °F

Lim. expl.

42 %, 63 °F

técnica(s)

GC/GC: suitable

Impurezas

Dnases, none detected
 RNases, none detected
 insoluble matter, passes filter test
 phosphatases, none detected
 proteases, none detected
≤0.001% free acid (as CH3COOH)

resíduo de evaporação

≤0.005%

cor

colorless

índice de refração

n20/D 1.479 (lit.)
n20/D 1.479

p.e.

189 °C (lit.)

pf

16-19 °C (lit.)

solubilidade

H2O: miscible (completely)

densidade

1.10 g/mL (lit.)

traços de cátion

Al: ≤0.5 mg/kg
Ba: ≤0.1 mg/kg
Bi: ≤0.1 mg/kg
Ca: ≤0.5 mg/kg
Cd: ≤0.05 mg/kg
Co: ≤0.02 mg/kg
Cr: ≤0.02 mg/kg
Cu: ≤0.02 mg/kg
Fe: ≤0.5 mg/kg
K: ≤0.5 mg/kg
Li: ≤0.1 mg/kg
Mg: ≤0.1 mg/kg
Mn: ≤0.02 mg/kg
Mo: ≤0.1 mg/kg
Na: ≤1 mg/kg
Ni: ≤0.5 mg/kg
Pb: ≤0.1 mg/kg
Sr: ≤0.1 mg/kg
Zn: ≤0.1 mg/kg

cadeia de caracteres SMILES

CS(C)=O

λ

neat

Absorção UV

λ: 280 nm Amax: 0.22

adequação

suitable for molecular biology

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

chave InChI

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

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Descrição geral

Dimethyl sulfoxide (DMSO) is an effective aprotic solvent. It is colorless, odorless and hygroscopic in nature. DMSO enhance the permeability of various hydrophilic and lipophilic permeants.[1] It is one of the widely used solvents in the laboratory.[2]

Aplicação

Dimethyl sulfoxide (DMSO) has been used as a vehicle for test compounds in various experimental studies.[3][4] It has also been used as a solvent during amyloid β (Aβ) aggregation protocol for resolubilization of peptide to maintain its dissociated state.[5]

Atenção

Resfria-se intensamente com facilidade e derrete novamente de forma lenta em temperatura ambiente. O produto solidificado pode ser liquefeito novamente aquecendo-o até atingir a temperatura ambiente, sem causar dano ao produto.

Outras notas

Polybrene / DMSO-assisted gene transfer[6]

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

188.6 °F - closed cup

Ponto de fulgor (°C)

87 °C - closed cup

Equipamento de proteção individual

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
BCCM8451
BCCM1815
BCCL0999
BCCL9737
BCCK1723

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Supelco

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R Aubin et al.
Methods in molecular biology (Clifton, N.J.), 7, 35-43 (1991-01-01)
Efforts to expand the current repertory of cell types amenable to transfection have often been thwarted by a common obstacle-namely, the low tolerance displayed by the recipient cells toward the gene-transfer regimen itself. As a result, several laboratories have turned
Developmental toxicity assay using high content screening of zebrafish embryos
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Questions

1–10 of 11 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  3. Where does DMSO come from?

    1 answer

    1. DMSO is known to have been isolated from tree bark in the past. It is now a commericially synthesized solvent.

      Helpful?

  4. What is Sure/Seal™ packaging?

    1 answer

    1. The Aldrich Sure/Seal™ packaging system is useful in the handling and storage of air-sensitive reagents.

      Helpful?

  5. Does DMSO have any synthetic utility?

    1 answer

    1. DMSO has been used to oxidize thiols and disulfides to sulfonic acids, hydrolysis of epoxides, thioalkylation of phenols, and oxidation of primary alcohols and halides, and esters of primary alcohols to aldehydes.

      Helpful?

  6. Dimethyl sulfoxide (DMSO) should be a liquid.  Why did it arrive as a solid?

    1 answer

    1. DMSO supercools easily, and re-melts slowly at room temperature. The melting point is 16-19 °C. The solidified product can be re-liquefied by warming to room temperature without detriment to the product.

      Helpful?

  7. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  8. What is the DMSO dissolved in?

    1 answer

    1. DMSO is not dissolved in any solvent. It is a pure chemical compound that is a liquid at room temperature.

      Helpful?

  9. Is Dimethyl sulfoxide a sterile product?

    1 answer

    1. No, this product is not considered sterile.  Product Nos. D2560 and D2438 are sterile-filtered.

      Helpful?

  10. What type of filter is used to sterile-filter Dimethyl sulfoxide (DMSO)?

    1 answer

    1. DMSO can be sterile-filtered through a 0.2 micron PTFE filter. The sterility testing is per the current US Pharmacopoeia method.

      Helpful?

1–10 of 11 Questions  

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