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Merck

42623

Butyryl-L-carnitine

≥97.0% (TLC)

Sinônimo(s):

(2R)-3-Carboxy-N,N,N-trimethyl-2-(1-oxobutoxy)-1-propanaminium inner salt, Butanoyl-L-carnitine, C4-Carnitine

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Sobre este item

Fórmula empírica (Notação de Hill):
C11H21NO4
Número CAS:
25576-40-3
Peso molecular:
231.29
UNSPSC Code:
41116107
PubChem Substance ID:
329756249
NACRES:
NA.26
MDL number:
MFCD01674827

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Nome do produto

Butyryl-L-carnitine, ≥97.0% (TLC)

SMILES string

C[N+](C)(C)C[C@H](OC(CCC)=O)CC([O-])=O

InChI key

QWYFHHGCZUCMBN-SECBINFHSA-N

InChI

1S/C11H21NO4/c1-5-6-11(15)16-9(7-10(13)14)8-12(2,3)4/h9H,5-8H2,1-4H3/t9-/m1/s1

assay

≥97.0% (TLC)

form

powder, crystals or chunks

optical activity

[α]/D -23±2°, c = 1 in H2O

color

white to off-white

storage temp.

2-8°C

Quality Level

100

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Este Item
504055108551371
Butyryl-L-carnitine ≥97.0% (TLC)

Sigma-Aldrich

42623

Butyryl-L-carnitine

2-Methylbutyryl-L-carnitine ≥97.0% (HPLC)

Sigma-Aldrich

50405

2-Methylbutyryl-L-carnitine

Isobutyryl-L-carnitine ≥97.0% (HPLC)

Sigma-Aldrich

51085

Isobutyryl-L-carnitine

Isovaleryl-L-carnitine ≥94.0% (HPLC)

Sigma-Aldrich

51371

Isovaleryl-L-carnitine

form

powder, crystals or chunks

form

powder or crystals

form

powder

form

powder or crystals

assay

≥97.0% (TLC)

assay

≥97.0% (HPLC)

assay

≥97.0% (HPLC)

assay

≥94.0% (HPLC)

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

optical activity

[α]/D -23±2°, c = 1 in H2O

optical activity

[α]/D -20±2°, c = 0.1 in H2O

optical activity

[α]/D -22±2°, c = 1 in H2O

optical activity

[α]/D -23±2°, c = 1 in H2O

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

color

white to off-white

color

white to off-white

color

white

color

white to off-white

Application


  • Lead exposure induces metabolic reprogramming in rat models.: This study by Mani MS et al. investigates the metabolic effects of lead exposure in rat models, focusing on the biochemical pathways affected. The research highlights the role of butyryl-ʟ-carnitine in counteracting lead-induced metabolic disruptions, suggesting its potential therapeutic applications in mitigating heavy metal toxicity (Mani et al., 2020).

Biochem/physiol Actions

Butyrylcarnitine is elevated in patients with Acyl-CoA dehydrogenase, short-chain (SCAD) deficiency, in infants with acute acidosis and generalized muscle weakness and in middle-aged patients with chronic myopathy localized in muscle[1][2][3]; very long chain Acyl-CoA dehydrogenase deficiency[4], and celiac disease[5].

Classe de armazenamento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análise (COA)

Lot/Batch Number
BCCN2262
BCCB3203
BCBZ6118
BCBP1876V
BCBP1876

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R Golan et al.
International journal of andrology, 6(4), 349-357 (1983-08-01)
Bioautography of human semen demonstrated the presence of L-carnitine, acetylcarnitine, propionylcarnitine and C4-acylcarnitines (butyrylcarnitines). In studies designed to ascertain the organs secreting these compounds into semen it was found that: Quantitative analyses of semen obtained pre- and post-vasectomy showed markedly
Sarah P Young et al.
Clinica chimica acta; international journal of clinical chemistry, 337(1-2), 103-113 (2003-10-22)
Homozygosity and compound heterozygosity for the short chain acyl-CoA dehydrogenase (SCAD) gene sequence variants 625G-->A and 511C-->T are associated with ethylmalonic aciduria (EMA), a biochemical indicator of SCAD deficiency. The clinical and biochemical implications of these variants are not fully
Josiane Joseph et al.
Metabolites, 8(4) (2018-10-05)
Duchenne muscular dystrophy (DMD) is a musculoskeletal disorder that causes severe morbidity and reduced lifespan. Individuals with DMD have an X-linked mutation that impairs their ability to produce functional dystrophin protein in muscle. No cure exists for this disease and
S Benito et al.
The Analyst, 143(18), 4448-4458 (2018-08-29)
Pediatric chronic kidney disease (CKD) is a clinical syndrome characterized by renal hypofunction occurring due to gradual and irreversible kidney damage that can further progress over time. New biomarkers may help early diagnosis of pediatric patients suffering from CKD and
A Bhala et al.
The Journal of pediatrics, 126(6), 910-915 (1995-06-01)
We identified two additional patients with short-chain acyl-coenzyme A (CoA), further characterized the clinical and biochemical features of this defect, and compared it with other fatty acid oxidation defects. We have measured the in vitro short-chain acyl-coenzyme A dehydrogenase (SCAD)
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