Merck
Todas as fotos(1)

57600

Sigma-Aldrich

Interleukin-2 human

recombinant, expressed in E. coli, ~10000 U/mL

Sinônimo(s):
IL-2, hIL-2, TCGF
Número CAS:
Número MDL:
NACRES:
NA.32

Nível de qualidade

100

fonte biológica

human

recombinante

expressed in E. coli

forma

liquid

peso molecular

Mr ~15500

embalagem

vial of 1 mL

concentração

~10000 U/mL

cor

colorless

nº de adesão UniProt

enviado em

dry ice

temperatura de armazenamento

−70°C

Gene Information

human ... IL2(3558)

Categorias relacionadas

Ações bioquímicas/fisiológicas

Promotes the growth of IL-2 dependent lymphocytes. Amino acid sequence of IL-2.

Embalagem

One vial contains 10′000 Units

Atenção

Stable at −20 °C; prepare appropriate aliquots and avoid repeated freezing and thawing, since aggregation may occur resulting in apparent loss of activity.

Definição da unidade

1 U corresponds to the unit activity in the colorimetric MTT-assay with CTLL-2 cells.

forma física

Clear; colorless solution in Dulbecco-PBS; containing 1 mg BSA/mL.

Outras notas

Sales restrictions may apply.

Código de classe de armazenamento

12 - Non Combustible Liquids

WGK

WGK 3

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Certificado de análise

Insira o número de lote para pesquisar o Certificado de análise (COA).

Certificado de origem

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Interleukin 2.
K A Smith
Annual review of immunology, 2, 319-333 (1984-01-01)
S Gillis et al.
Journal of immunology (Baltimore, Md. : 1950), 120(6), 2027-2032 (1978-06-01)
Several soluble factors have recently been associated with the proliferation and differentiation of thymus-derived lymphocytes. One of these factors present in medium conditioned by T cell mitogen-stimulated lymphocytes has the ability to promote the long-term culture of normal and antigen-specific
R J Robb et al.
Proceedings of the National Academy of Sciences of the United States of America, 81(20), 6486-6490 (1984-10-01)
Human interleukin 2 was separated into multiple molecular forms by selective immunoaffinity chromatography and chromatofocusing. For the most part, this heterogeneity was attributed to variations in glycosylation of the threonine residue in position 3 of the polypeptide chain. The various
Nabil Ahmed et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 33(15), 1688-1696 (2015-03-25)
The outcome for patients with metastatic or recurrent sarcoma remains poor. Adoptive therapy with tumor-directed T cells is an attractive therapeutic option but has never been evaluated in sarcoma. We conducted a phase I/II clinical study in which patients with
Cecilie Brekke Rygh et al.
PloS one, 9(9), e108414-e108414 (2014-10-01)
There are currently no established radiological parameters that predict response to immunotherapy. We hypothesised that multiparametric, longitudinal magnetic resonance imaging (MRI) of physiological parameters and pharmacokinetic models might detect early biological responses to immunotherapy for glioblastoma targeting NG2/CSPG4 with mAb9.2.27

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