63559

Sigma-Aldrich

D-Mannitol

BioUltra, ≥99.0% (sum of enantiomers, HPLC)

Sinônimo(s):
Mannite
Empirical Formula (Hill Notation):
C6H14O6
Número CAS:
Peso molecular:
182.17
Beilstein/REAXYS Number:
1721898
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.25

linha de produto

BioUltra

Nível de qualidade

200

teor

≥99.0% (sum of enantiomers, HPLC)

atividade óptica

[α]20/D +24.0±1° in borax solution acc. to Ph Eur

Impurezas

insoluble matter, passes filter test
reducing sugars, complies
≤0.0072% free acid (as CH3COOH)

resíduo de ignição

≤0.01% (as SO4)

perda

≤0.05% loss on drying, 20 °C (HV)

pH

5.0-6.5 (25 °C, 1 M in H2O)

pf

166-168 °C
167-170 °C (lit.)

solubilidade

H2O: 1 M at 20 °C, clear, colorless

traços de ânion

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

traços de cátion

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤1 mg/kg
Pb: ≤1 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

1 M in H2O

Absorção UV

λ: 260 nm Amax: 0.04
λ: 280 nm Amax: 0.04

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1

InChI key

FBPFZTCFMRRESA-KVTDHHQDSA-N

Procurando produtos similares? Visit Guia de comparação de produtos

Aplicação

D-Mannitol is used as an osmolyte and transport facilitator in a variety of biological in vivo and in vitro applications, such as improvement of blood-brain barrier transport and hyperosmolar therapy. D-Mannitol is used as a substrate to identify, differentiate and characterized enzymes such as mannitol dehydrogenase(s). D-Mannitol is used in identify mannitol metabolizing bacteria.

Ações bioquímicas/fisiológicas

A sugar alcohol sweet tastant. Used in sweetness inhibition studies.

Outras notas

Used in discontinuous gradient centrifugation for purification of plant protoplasts. Plasmolyticum that reversibly inhibits phenylalanine ammonia-lyase activity of protoplasts at concentrations exceeding 50 mM. Component of the liquid stationary phase in the GLC separation of nitroxylene and xylenol isomers.

storage_class_code

11 - Combustible Solids

WGK Alemanha

WGK 2

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificado de análise

Certificado de origem

Anna Stepanova et al.
Antioxidants & redox signaling, 31(9), 608-622 (2019-05-01)
Aims: Brain ischemia/reperfusion (I/R) is associated with impairment of mitochondrial function. However, the mechanisms of mitochondrial failure are not...
B.G. Hughes
Biochem. Physiol. Pflanz., 172, 223-223 (1978)
B. Fritig
Phytochemistry, 16, 895-895 (1977)
Separation behaviour of some isomeric organic compounds on sugars, sugar alcohols and their mixed phases by gas-liquid chromatography.
Ono, A.
Journal of Chromatography A, 197, 251-251 (1980)
Diana Bilton et al.
Thorax, 69(12), 1073-1079 (2014-09-24)
Bronchiectasis is characterised by excessive production of mucus and pulmonary exacerbations. Inhaled osmotic agents may enhance mucociliary clearance, but few long-term clinical trials have been conducted. To determine the impact of inhaled mannitol on exacerbation rates in patients with non-cystic...

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica