63559

D-Mannitol

BioUltra, ≥99.0% (sum of enantiomers, HPLC)

• Synonym(s): Mannite
• Empirical Formula (Hill Notation): C₆H₁₄O₆
• CAS Number: 69-65-8
• Molecular Weight: 182.17
• Beilstein: 1721898
• Número EC: 200-711-8
• Número MDL: MFCD00064287
• ID de substância PubChem: 57651947
• NACRES: NA.25

Properties

• linha de produto: BioUltra
• Nível de qualidade: 200
• teor: ≥99.0% (sum of enantiomers, HPLC)
• forma: powder
• atividade óptica: [α]20/D +24.0±1° in borax solution acc. to Ph Eur
• Impurezas: insoluble matter, passes filter test; reducing sugars, complies; ≤0.0072% free acid (as CH₃COOH)
• resíduo de ignição: ≤0.01% (as SO₄)
• perda: ≤0.05% loss on drying, 20 °C (HV)
• pH: 5.0-6.5 (25 °C, 1 M in H₂O)
• pf: 166-168 °C; 167-170 °C (lit.)
• solubilidade: H₂O: 1 M at 20 °C, clear, colorless
• traços de ânion: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• traços de cátion: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤1 mg/kg; Pb: ≤1 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• λ: 1 M in H₂O
• Absorção UV: λ: 260 nm A_max: 0.04; λ: 280 nm A_max: 0.04
• SMILES string: OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
• InChI: 1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1
• InChI key: FBPFZTCFMRRESA-KVTDHHQDSA-N

Description

Aplicação

D-Mannitol is used as an osmolyte and transport facilitator in a variety of biological in vivo and in vitro applications, such as improvement of blood-brain barrier transport and hyperosmolar therapy. D-Mannitol is used as a substrate to identify, differentiate and characterized enzymes such as mannitol dehydrogenase(s). D-Mannitol is used in identify mannitol metabolizing bacteria.

Ações bioquímicas/fisiológicas

A sugar alcohol sweet tastant. Used in sweetness inhibition studies.

Outras notas

Used in discontinuous gradient centrifugation for purification of plant protoplasts[1]. Plasmolyticum that reversibly inhibits phenylalanine ammonia-lyase activity of protoplasts at concentrations exceeding 50 mM[2]. Component of the liquid stationary phase in the GLC separation of nitroxylene and xylenol isomers[3].

Safety Information

• Código de classe de armazenamento: 11 - Combustible Solids
• WGK: WGK 1
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)