Merck
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87917

Sigma-Aldrich

Tetramethylrhodamine ethyl ester perchlorate

suitable for fluorescence, ≥90% (HPCE)

Synonym(s):
TMRE, TMRE perchlorate
Empirical Formula (Hill Notation):
C26H27ClN2O7
CAS Number:
Molecular Weight:
514.95
Número MDL:
ID de substância PubChem:
NACRES:
NA.32

Nível de qualidade

100

teor

≥90% (HPCE)

forma

solid

solubilidade

DMSO: soluble
alcohols: soluble

fluorescência

λex 540 nm; λem 595 nm in DMSO

adequação

suitable for fluorescence

temperatura de armazenamento

2-8°C

SMILES string

[O-]Cl(=O)(=O)=O.CCOC(=O)c1ccccc1-c2c3ccc(cc3[o+]c4cc(ccc24)N(C)C)N(C)C

InChI

1S/C26H27N2O3.ClHO4/c1-6-30-26(29)20-10-8-7-9-19(20)25-21-13-11-17(27(2)3)15-23(21)31-24-16-18(28(4)5)12-14-22(24)25;2-1(3,4)5/h7-16H,6H2,1-5H3;(H,2,3,4,5)/q+1;/p-1

InChI key

NBAOBNBFGNQAEJ-UHFFFAOYSA-M

Descrição geral

Tetramethylrhodamine ethyl ester perchlorate (TMRE), also known as TMRE perchlorate, is a potential mitochondrial dye. TMRE staining process is reversible, and it doesn’t affect cell proliferation and viability.

The sorted cells containing TMRE perchlorate don’t interfere with the subsequent functional assays and hence are a preferred choice for the enrichment of functionally active, unbiased cell populations.

Aplicação

Tetramethylrhodamine ethyl ester perchlorate (TMRE) is used to study the effects of high glucose in inducing mitochondrial morphology and metabolic changes.

TMRE perchlorate is also used to study Fullerene C 60 penetration into Leukemic Cells and the subsequent photoinduced Cytotoxic Effects.

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

Outras notas

Potential-sensitive probe for measuring membrane potential changes in mitochondria

Pictogramas

Exclamation mark

Palavra indicadora

Warning

Classificações de perigo

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Código de classe de armazenamento

13 - Non Combustible Solids

WGK

WGK 3

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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