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Documentos Principais

95209

Sigma-Aldrich

Ácido L-ascórbico

BioUltra, ≥99.5% (RT)

Sinônimo(s):

Ácido L-treoascórbico, Fator antiescorbútico, Vitamina C

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About This Item

Fórmula empírica (Notação de Hill):
C6H8O6
Número CAS:
Peso molecular:
176.12
Beilstein:
84272
Número CE:
Número MDL:
Código UNSPSC:
12352205
ID de substância PubChem:
NACRES:
NA.79
Preço e disponibilidade não estão disponíveis no momento.

fonte biológica

synthetic

Nível de qualidade

grau

biotech. grade

linha de produto

BioUltra

Ensaio

≥99.5% (RT)

Formulário

powder or crystals

Impurezas

insoluble matter, passes filter test

resíduo de ignição

≤0.05% (as SO4)

perda

≤0.05% loss on drying, 20 °C (HV)

cor

white to off-white

pH

1.0-2.5 (25 °C, 1 M in H2O)

pf

190-194 °C (dec.)

solubilidade

H2O: 1 M at 20 °C, clear, colorless

traços de ânion

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤20 mg/kg

traços de cátion

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤25 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

Absorção

cut-off at 306 nm in H2O at 1 M

cadeia de caracteres SMILES

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

chave InChI

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Informações sobre genes

human ... SLC23A2(9962)

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Descrição geral

L-Ascorbic acid, also known as vitamin C, is a water-soluble vitamin.[1] It is naturally present in a variety of foods such as citrus fruits and vegetables. It is present only in minimal amount in milk.[2]

Aplicação

L-Ascorbic acid has been used as an antioxidant supplement in incubation solution for dissected and sliced brain sections.[3][4] It has also been used as a supplement in phosphate-buffered saline (PBS) wash buffer during oxidative GFP chromophore formation.[5]

Ações bioquímicas/fisiológicas

L-Ascorbic acid (Vitamin C) acts as a potential anti-oxidant[6] and reducing agent.[7] It prevents bacterial mutagenesis induced by N-nitroso compounds.[8] In plants, vitamin C elicits several cellular processes such as growth, apoptosis, pathogen responses, hormone responses, flowering and senescence, and protection against environmental stresses. [7] Vitamin C deficiency is associated with the development of scurvy, prominent - gingivitis, perifollicular hemorrhages, poor wound healing, petechiae and ecchymosis.[2]

Outras notas

Denaturation of proteinscitation; Dimeric association of E. coli RNA polymerase α subunits, studied by cleavage of single cysteine α subunits conjugated to Fe-BABEcitation.
Denaturation of proteins[9]; Dimeric association of E. coli RNA polymerase α subunits, studied by cleavage of single cysteine α subunits conjugated to Fe-BABE[10].

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


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Slide 1 of 7

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F C Brown et al.
Neurochemical research, 3(3), 357-366 (1978-06-01)
Under conditions that are optimum for DbetaH, ascorbic acid denatures serum albumin, gamma-globulin, catalase, and DbetaH. With ascrobate plus Cu2+, the proteins are almost completely destroyed. Pyrazole protects DbetaH and albumin, but not catalase. Superoxide dismutase (SOD) is not denatured
Calcium Imaging Techniques In Vitro to Explore the Role of Dendrites in Signaling Physiological Action Potential Patterns
Bonnan A, et al.
The Journal of applied nutrition (1953)
Calcium Imaging Techniques In Vitro to Explore the Role of Dendrites in Signaling Physiological Action Potential Patterns
Neuromethods, 165-187 (2012)
A family of mammalian Na+-dependent L-ascorbic acid transporters
Tsukaguchi H, et al.
Nature, 399(6731), 70-70 (1999)
Inhibition by L-ascorbate of bacterial mutagenesis induced by two N-nitroso compounds
Guttenplan JB
Nature, 268(5618), 368-368 (1977)

Questions

  1. The material is in powder or crystal form and whether it’s suitable for hydrogen evolution reaction (HER) measurements?

    1 answer
    1. The material specification is 'powder or crystals', which means it can vary from batch to batch. Ascorbic acid can donate electrons, facilitating the reduction of protons (H?) to hydrogen gas (H?). Its ability to undergo oxidation makes it a suitable candidate for these hydrogen evolution reactions. This product has not been tested internally for this application. Given the high purity of this material, it is likely suitable, but this would need to be determined by the end user.

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