Merck
  • A2129
All Photos(1)

A2129

Sigma-Aldrich

γ-Aminobutyric acid

≥99%

Synonym(s):
GABA, Gammalon, gamma-Aminobutyric acid, 3-Carboxypropylamine, 4-Aminobutanoic acid, Piperidic acid, Piperidinic acid
Linear Formula:
NH2(CH2)3COOH
CAS Number:
Molecular Weight:
103.12
Beilstein:
906818
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.32

Nível de qualidade

teor

≥99%

forma

crystals

condição de armazenamento

(Tightly closed. Dry.)

cor

colorless

pf

195 °C (dec.) (lit.)

solubilidade

water: 50 mg/mL, clear, colorless

SMILES string

NCCCC(O)=O

InChI

1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)

InChI key

BTCSSZJGUNDROE-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

1 of 4

This Item
PHL83415PHL8341503835
γ-Aminobutyric acid ≥99%

Sigma-Aldrich

A2129

γ-Aminobutyric acid

γ-Aminobutyric acid phyproof® Reference Substance

PHL83415

γ-Aminobutyric acid

γ-Aminobutyric acid phyproof® Reference Substance

PHL83415

γ-Aminobutyric acid

γ-Aminobutyric acid analytical standard

Supelco

03835

γ-Aminobutyric acid

assay

≥99%

assay

≥98.0% (HPLC)

assay

≥98.0% (HPLC)

assay

≥97.0% (HPLC)

form

crystals

form

crystals

form

crystals

form

-

storage condition

(Tightly closed. Dry.)

storage condition

-

storage condition

-

storage condition

-

color

colorless

color

-

color

-

color

-

solubility

water: 50 mg/mL, clear, colorless

solubility

-

solubility

-

solubility

-

Quality Level

200

Quality Level

-

Quality Level

-

Quality Level

100

Descrição geral

γ-Aminobutyric acid (GABA) is a non-amino protein. It is found in plants, animals, and microorganisms. GABA has been used in pharma and food industries as a component of cheese, shochu, gabaron tea, and gammalone.
Research area: Neuroscience

Aplicação

γ-Aminobutyric acid (GABA) has been used:
  • in the preparation of GABA–BSA (bovine serum albumin)–GA (glutaraldehyde) conjugate, which is used as a control for GABA immunostaining
  • in the macromolecule suppressed detection of GABA by magnetic resonance spectroscopy (MRS)
  • in the intraintestinal application of GABA in order to increase intraluminal fluid secretion

Ações bioquímicas/fisiológicas

GABA (γ-Aminobutyric acid) is an amino acid that functions as an inhibitory neurotransmitter in the central nervous system and as a neuromodulator in some peripheral tissues. It binds to the GABAA receptor and inhibits the activity of signal-receiving neurons. The GABAA receptors are found to form a channel in the cell membranes of neurons. Upon binding of GABA, the receptor is activated to allow the passage of negatively charged molecules, such as chloride ions, into the cell. This results in a lowering of the excitability of the cell.
GABAergic neurons involve myorelaxation, anxiolytic treatment, sedation, and anesthetics. GABA can also influence heart rate and blood pressure.
GABA improves plasma concentration, growth hormone, and protein synthesis in the brain. It also plays a role in reducing blood pressure in humans. GABA acts as a potent hypotensive, diuretic, and antidiabetic agent. It also regulates serum lipids levels and the sensation of pain.
Major inhibitory neurotransmitter in brain; GABAA and GABAB receptor agonist; increases Cl conductance.

Código de classe de armazenamento

11 - Combustible Solids

WGK

WGK 3

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service