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A2786

Sigma-Aldrich

Adenine

BioReagent, suitable for cell culture

Sinônimo(s):
Vitamin B4, 6-Aminopurine
Empirical Formula (Hill Notation):
C5H5N5
Número CAS:
Peso molecular:
135.13
Beilstein:
5777
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.75

Nível de qualidade

200

fonte biológica

synthetic

linha de produto

BioReagent

teor

≥99%

forma

powder

peso molecular

Mw 135.13 g/mol

aplicação(ões)

cell culture | mammalian: suitable

cor

white to off-white

pf

>360 °C (lit.)

solubilidade

0.5 M HCl: soluble 20 mg/mL, clear to slightly hazy, colorless to faintly yellow

temperatura de armazenamento

room temp

SMILES string

Nc1ncnc2[nH]cnc12

InChI

1S/C5H5N5/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H3,6,7,8,9,10)

InChI key

GFFGJBXGBJISGV-UHFFFAOYSA-N

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Descrição geral

Adenine is a purine nucleobase, synthesized from inosine monophosphate(IMP). It is a nitrogenous heterocyclic aromatic compound.

Aplicação

Adenine has been used:
  • a component of green medium used for the derivation of keratinocytes from plucked hair follicles
  • for the serial culture of adult murine keratinocytes
  • as a media component for SSEA4+ limbal stromal stem cell differentiation

Embalagem

5, 25, 100 g in poly bottle

Ações bioquímicas/fisiológicas

Adenine is a component of important biomolecules such as adenosine triphosphate (ATP), nicotinamide adenine dinucleotide (NAD) and flavin adenine dinucleotide (FAD). NAD and FAD forms the structure of DNA and RNA, and plays important role in protein synthesis. ATP is an energy source, that is essential for cellular respiration.

Pictogramas

Skull and crossbones

Palavra indicadora

Danger

Frases de perigo

Declarações de precaução

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK Alemanha

WGK 3

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Certificado de análise

Certificado de origem

The
Vander's Human Physiology, The Mechanisms of Body Function: Medicine, Human anatomy (2016)
Method for the Derivation of Induced Pluripotent Stem Cells from Human Hair Follicle Keratinocytes
Atlas of Human Pluripotent Stem Cells, 127-137 (2012)
Limbal stromal tissue specific stem cells and their differentiation potential to corneal epithelial cells
Embryonic Stem Cell Protocols, 437-444 (2015)
Serial cultivation of primary adult murine keratinocytes
Epidermal Cells, 15-22 (2005)
Brian T Wilhelm et al.
Nature protocols, 5(2), 255-266 (2010-02-06)
Next-generation sequencing technologies are revolutionizing genomics research. It is now possible to generate gigabase pairs of DNA sequence within a week without time-consuming cloning or massive infrastructure. This technology has recently been applied to the development of 'RNA-seq' techniques for...

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