Merck
All Photos(1)

A4403

Sigma-Aldrich

L-Ascorbic acid

powder, suitable for cell culture, γ-irradiated

Synonym(s):
L-Threoascorbic acid, Antiscorbutic factor, Vitamin C
Empirical Formula (Hill Notation):
C6H8O6
CAS Number:
Molecular Weight:
176.12
Beilstein:
84272
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.75

fonte biológica

synthetic (organic)

Nível de qualidade

esterilidade

γ-irradiated

forma

powder

peso molecular

Mw 176.12 g/mol

technique(s)

cell culture | insect: suitable
cell culture | mammalian: suitable
cell culture | plant: suitable

cor

white to off-white

pH

1.0-2.5 (25 °C, 176 g/L in water)

pf

190-194 °C (dec.)

solubilidade

H2O: 10 mg/mL

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Gene Information

human ... SLC23A2(9962)

Looking for similar products? Visit Product Comparison Guide

Related Categories

Compare Similar Items

View Full Comparison

1 of 4

This Item
A750633034A2218
L-Ascorbic acid powder, suitable for cell culture, γ-irradiated

Sigma-Aldrich

A4403

L-Ascorbic acid

L-Ascorbic acid reagent grade, crystalline

Sigma-Aldrich

A7506

L-Ascorbic acid

L-Ascorbic acid puriss. p.a., ACS reagent, reag. ISO, Ph. Eur., 99.7-100.5% (oxidimetric)

Sigma-Aldrich

33034

L-Ascorbic acid

L-Ascorbic acid meets USP testing specifications

Sigma-Aldrich

A2218

L-Ascorbic acid

form

powder

form

crystalline

form

solid

form

solid

pH

1.0-2.5 (25 °C, 176 g/L in water)

pH

1.0-2.5 (25 °C, 176 g/L in water)

pH

2.1-2.6 (20 °C, 5%)

pH

1.0-2.5 (25 °C, 176 g/L in water)

mp

190-194 °C (dec.)

mp

190-194 °C (dec.)

mp

190-194 °C (dec.)

mp

190-194 °C (dec.)

solubility

H2O: 10 mg/mL

solubility

water: soluble 50 mg/mL

solubility

water: soluble 176 g/L at 20 °C

solubility

water: soluble 176 g/L at 20 °C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

biological source

synthetic (organic)

biological source

synthetic

biological source

synthetic

biological source

synthetic

Descrição geral

L-ascorbic acid is an unsaturated γ-lactone ring containing an enediol configuration (–COH=COH) attached with a carbonyl group.

Aplicação

For use in cell culture applications as an antioxidant and to regenerate tocopherol.
L-ascorbic acid has been used:
  • in an osteogenic supplement for the growth of cells
  • as a component in the differentiation media
  • in WS-MSCs (Werner syndrome-mesenchymal stem cells) to study rescuing properties of ascorbic acid on aging defects

Ações bioquímicas/fisiológicas

L-ascorbic acid mainly exhibits antioxidant properties. It protects plants from oxidative stress and mammals from diseases associated with oxidative stress. L-ascorbic acid mainly protects from hydroxyl radicals, superoxide and singlet oxygen. In addition, it also reduces the membrane-linked antioxidant α-tocopherol (oxidised form). L-Ascorbic acid enhances endothelium-dependent vasodilation in various disorders, including diabetes, coronary artery disease, hypertension and chronic heart failure.

Código de classe de armazenamento

11 - Combustible Solids

WGK

WGK 3

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service