A5955

Sigma-Aldrich

Antibiotic Antimycotic Solution (100×), Stabilized

with 10,000 units penicillin, 10 mg streptomycin and 25 μg amphotericin B per mL, 0.1 μm filtered, BioReagent, suitable for cell culture

Número MDL:
NACRES:
NA.76

Nível de qualidade

200

esterilidade

0.1 μm filtered

linha de produto

BioReagent

forma

suspension

aplicação(ões)

cell culture | mammalian: suitable

Impurezas

endotoxin, tested

cor

yellow

Setor em destaque

Agriculture

Modo de ação

cell wall synthesis | interferes

espectro de atividade do antibiótico

Gram-negative bacteria
Gram-positive bacteria
fungi
yeast

enviado em

dry ice

temperatura de armazenamento

−20°C

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Aplicação

This solution is formulated to contain 10,000 units penicillin, 10 mg streptomycin and 25μg Amphotericin B per mL, and is solubilized in a proprietary citrate buffer. It is recommended for use in cell culture applications at 10mL/L.
Antibiotic antimycotic solution has been used as a supplement in different types of cell culture media.

Ações bioquímicas/fisiológicas

Mode of Action: Penicillin acts by inhibiting bacterial cell-wall synthesis. Streptomycin inhibits prokaryote protein synthesis by preventing the transition from initiation complex to chain-elongating ribosome and causes miscoding. Amphotericin B interferes with fungal membrane permeability by forming channels in the membranes and causing small molecules to leak out.

Antimicrobial spectrum: Includes Gram-negative bacteria, Gram-positive bacteria, fungi and yeasts.

Pictogramas

Health hazard

Palavra indicadora

Danger

Frases de perigo

hazcat

Resp. Sens. 1 - Skin Sens. 1

storage_class_code

12 - Non Combustible Liquids

WGK Alemanha

WGK 2

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Certificado de análise

Certificado de origem

Alessandro Taloni et al.
Scientific reports, 7(1), 3748-3748 (2017-06-18)
Classification of morphological features in biological samples is usually performed by a trained eye but the increasing amount of available digital images calls for semi-automatic classification techniques. Here we explore this possibility in the context of acrosome morphological analysis during...
Kinue Aihara et al.
Kidney international, 64(4), 1283-1291 (2003-09-13)
Crystal formation and retention are critical events for the formation of kidney stones. Oxalate and calcium oxalate (CaOx) crystals are injurious to renal epithelium, and membranes of injured cells promote crystal adherence and retention. Calcium phosphate (CaP) is the most...
Qingqing Dai et al.
Journal of inflammation research, 12, 335-343 (2020-01-08)
Neutrophil infiltration and release of the abundant human neutrophil peptides (HNP) are a common clinical feature in critically ill patients. We tested a hypothesis that different cell types respond to HNP differently in lung microenvironment that may influence the host...
Barbara Teuchner et al.
Cornea, 38(8), 1011-1016 (2019-04-02)
N-chlorotaurine (NCT) is an anti-infective belonging to the class of chloramines and an investigative drug for the topical treatment of keratoconjunctivitis. The aim of the present study was to demonstrate its efficacy against Acanthamoeba and Candida in corneas infected ex...
Sai Zhang et al.
Materials science & engineering. C, Materials for biological applications, 79, 687-696 (2017-06-21)
To engineer bone tissue, it is crucial to design scaffolds with micro- and nano-sized architecture imitating approximate hierarchical structure of native bone, and afford desirable biological properties by introducing biocompatible polymers and bioceramics into the scaffolds. Here, a novel scaffold...

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