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Merck

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A7506

Ácido L-ascórbico

reagent grade, crystalline

Sinônimo(s):

Ácido L-treoascórbico, Fator antiescorbútico, Vitamina C

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Para você/SKUDisponibilidadePreço
25 g

Disponível para envio HOJEdeCajamar

R$ 393,00
100 g

Disponível para envio HOJEdeCajamar

R$ 452,00
500 g

Disponível para envio HOJEdeCajamar

R$ 1.008,00
1 kg

Previsão de entrega em05 de agosto de 2026deCajamar

R$ 1.460,00
5 kg

Previsão de entrega em05 de agosto de 2026deCajamar

R$ 4.510,00

Sobre este item

Fórmula linear:
C6H8O6
Número CAS:
Peso molecular:
176.12
UNSPSC Code:
12352209
NACRES:
NA.26
PubChem Substance ID:
EC Number:
200-066-2
Beilstein/REAXYS Number:
84272
MDL number:
Assay:
≥98% ( with iodine, titration)
Form:
crystalline
Grade:
reagent grade

R$ 393,00


Disponível para envio HOJEDetalhes


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biological source

synthetic

Quality Segment

grade

reagent grade

assay

≥98% ( with iodine, titration)

form

crystalline

technique(s)

HPLC: suitable, cell culture | stem cell: suitable

color

white to slightly yellow

pH

1.0-2.5 (25 °C, 176 g/L in water)

mp

190-194 °C (dec.)

solubility

water: soluble 50 mg/mL

storage temp.

room temp

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Gene Information

human ... SLC23A2(9962)

General description

L-Ascorbic acid biosynthetic pathway varies in plants, animals and fungi. It is synthesized from L-gulono-1,4-lactone by the action of enzyme L-gulono-1,4-lactone oxidase (GLO).

Application

L-Ascorbic acid has been used:
  • as a chondrogenic medium component for culturing bone-derived mesenchymal stem cells (BMSCs)(149)
  • as a reference standard in high-performance liquid chromatography system (HPLC)(150)
  • to test its effect on human gastric cancer GES-1 and AGS cells(151)

Biochem/physiol Actions

Ascorbic Acid, also known as Vitamin C, is a six-carbon lactone produced by plants and some animal species but not by humans and other primates. Ascorbic acid functions as an enzymatic cofactor for multiple enzymes, serving as an electron donor for monooxygenases and dioxygenases. Ascorbic acid also functions as a powerful antioxidant, particularly in regards to reactive oxygen species.
L-Ascorbic acid deficiency is associated with lack of L-gulono-1,4-lactone oxidase (GLO) enzyme. It elicits antioxidant functionality and gets oxidized to dehydroascorbate via ascorbyl radical intermediate. L-Ascorbic acid is essential for maintaining the redox balance. It is a cofactor for dopamine-β-hydroxylase and favors T cell proliferation, protects immune system and provides relief in common cold.

Disclaimer

May darken in storage.

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Este Item
A440333034255564
grade

reagent grade

grade

-

grade

ACS reagent, puriss. p.a.

grade

ACS reagent

assay

≥98% ( with iodine, titration)

assay

-

assay

99.7-100.5% (oxidimetric)

assay

≥99%

form

crystalline

form

powder

form

solid

form

crystals or granules, powder or chunks

storage temp.

room temp

storage temp.

-

storage temp.

-

storage temp.

-

solubility

water: soluble 50 mg/mL

solubility

H2O: 10 mg/mL

solubility

water: soluble 176 g/L at 20 °C

solubility

water: soluble 176 g/L at 20 °C

pH

1.0-2.5 (25 °C, 176 g/L in water)

pH

1.0-2.5 (25 °C, 176 g/L in water)

pH

2.1-2.6 (20 °C, 5%)

pH

1.0-2.5 (25 °C, 176 g/L in water)


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Classe de armazenamento

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Certificados de análise (COA)

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Questions

1–3 of 3 Questions  
  1. Can dissolved powder be autoclaved without losing its efficacy?

    1 answer
    1. Autoclaving causes Ascorbic acid solutions to decay rapidly.

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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