Merck
All Photos(5)

A7506

Sigma-Aldrich

Ácido L-ascórbico

reagent grade, crystalline

Synonym(s):
Ácido L-treoascórbico, Fator antiescorbútico, Vitamina C
Empirical Formula (Hill Notation):
C6H8O6
CAS Number:
Molecular Weight:
176.12
Beilstein:
84272
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.26

fonte biológica

synthetic

Nível de qualidade

grau

reagent grade

Ensaio

≥98% ( with iodine, titration)

forma

crystalline

technique(s)

HPLC: suitable
cell culture | stem cell: suitable

cor

white to slightly yellow

pH

1.0-2.5 (25 °C, 176 g/L in water)

pf

190-194 °C (dec.)

solubilidade

water: soluble 50 mg/mL

temperatura de armazenamento

room temp

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Gene Information

human ... SLC23A2(9962)

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This Item
A0278A4403255564
L-Ascorbic acid reagent grade, crystalline

Sigma-Aldrich

A7506

L-Ascorbic acid

L-Ascorbic acid reagent grade

Sigma-Aldrich

A0278

L-Ascorbic acid

L-Ascorbic acid powder, suitable for cell culture, γ-irradiated

Sigma-Aldrich

A4403

L-Ascorbic acid

L-Ascorbic acid ACS reagent, ≥99%

Sigma-Aldrich

255564

L-Ascorbic acid

grade

reagent grade

grade

reagent grade

grade

-

grade

ACS reagent

assay

≥98% ( with iodine, titration)

assay

≥98% (with Iodine, titration)

assay

-

assay

≥99%

form

crystalline

form

powder

form

powder

form

chunks, crystalline powder, crystals, granular

pH

1.0-2.5 (25 °C, 176 g/L in water)

pH

1.0-2.5 (25 °C, 176 g/L in water)

pH

1.0-2.5 (25 °C, 176 g/L in water)

pH

1.0-2.5 (25 °C, 176 g/L in water)

mp

190-194 °C (dec.)

mp

190-194 °C (dec.)

mp

190-194 °C (dec.)

mp

190-194 °C (dec.)

solubility

water: soluble 50 mg/mL

solubility

water: soluble 50 mg/mL

solubility

H2O: 10 mg/mL

solubility

water: soluble 176 g/L at 20 °C

Descrição geral

L-Ascorbic acid biosynthetic pathway varies in plants, animals and fungi. It is synthesized from L-gulono-1,4-lactone by the action of enzyme L-gulono-1,4-lactone oxidase (GLO).

Aplicação

L-Ascorbic acid has been used:
  • as a chondrogenic medium component for culturing bone-derived mesenchymal stem cells (BMSCs)(149)
  • as a reference standard in high-performance liquid chromatography system (HPLC)(150)
  • to test its effect on human gastric cancer GES-1 and AGS cells(151)

Ações bioquímicas/fisiológicas

Ascorbic Acid, also known as Vitamin C, is a six-carbon lactone produced by plants and some animal species but not by humans and other primates. Ascorbic acid functions as an enzymatic cofactor for multiple enzymes, serving as an electron donor for monooxygenases and dioxygenases. Ascorbic acid also functions as a powerful antioxidant, particularly in regards to reactive oxygen species.
L-Ascorbic acid deficiency is associated with lack of L-gulono-1,4-lactone oxidase (GLO) enzyme. It elicits antioxidant functionality and gets oxidized to dehydroascorbate via ascorbyl radical intermediate. L-Ascorbic acid is essential for maintaining the redox balance. It is a cofactor for dopamine-β-hydroxylase and favors T cell proliferation, protects immune system and provides relief in common cold.

Atenção

May darken in storage.

Código de classe de armazenamento

13 - Non Combustible Solids

WGK

WGK 1

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


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