All Photos(7)



Acetylcholinesterase from Electrophorus electricus (electric eel)

Type VI-S, lyophilized powder, 200-1,000 units/mg protein

AChE, Acetylcholine acetylhydrolase, Cholinesterase, Acetyl
CAS Number:
Enzyme Commission number:
Número EC:
Número MDL:


Type VI-S

Nível de qualidade



lyophilized powder

specific activity

200-1,000 units/mg protein

peso molecular

280 kDa


Protein, ≥60% biuret


20 mM Tris HCl buffer, pH 7.5: soluble 1.0 mg/mL, clear(lit.)


diagnostic assay manufacturing

temperatura de armazenamento


Looking for similar products? Visit Product Comparison Guide

Descrição geral

Molecular Weight: 280 kDa
Isoelectric Point: 5.5
Extinction Coefficient: E1% = 18.0 (280 nm)

Acetylcholinesterase from Electrophorus electricus is a tetramer composed of 4 equal subunits of 70 kDa each. Each subunit contains one active site. The enzyme is a glycoprotein containing hexosamines.


The enzyme from sigma has been used as a reference to to evaluate the effect of aspartame metabolites on hippocampal acetylcholinesterase activity. The enzyme has also been used in immobilization studies for the rapid detection of acetylthiocholine chloride.


500, 2000 units in glass bottle
10000 units in poly bottle

Ações bioquímicas/fisiológicas

Major degradative enzyme for acetylcholine in vivo. Converts acetylcholine + H2O to choline + acetic acid.

Definição da unidade

One unit will hydrolyze 1.0 μmole of acetylcholine to choline and acetate per min at pH 8.0 at 37 °C.

forma física

Lyophilized powder containing Tris buffer salts

Nota de preparo

This enzyme dissolves in 20 mM Tris-HCl buffer, pH 7.5 at 1 mg/mL concentration, yielding a clear solution.

Nota de análise

The activity obtained using acetylcholine as substrate is 30-100 times that obtained with butyrylcholine, using acetylcholinesterase from electric eel.

Código de classe de armazenamento

11 - Combustible Solids



Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

More Documents


Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service