Merck
  • C3506
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C3506

Sigma-Aldrich

Cytosine

≥99%

Synonym(s):
4-Amino-2-hydroxypyrimidine, 4-Aminopyrimidin-2-(1H)-one
Empirical Formula (Hill Notation):
C4H5N3O
CAS Number:
Molecular Weight:
111.10
Beilstein:
2637
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.51

fonte biológica

synthetic (organic)

Nível de qualidade

teor

≥99%

forma

powder

pf

>300 °C (lit.)

solubilidade

0.5 M HCl: 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow

SMILES string

NC1=NC(=O)NC=C1

InChI

1S/C4H5N3O/c5-3-1-2-6-4(8)7-3/h1-2H,(H3,5,6,7,8)

InChI key

OPTASPLRGRRNAP-UHFFFAOYSA-N

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Cytosine ≥99%

Sigma-Aldrich

C3506

Cytosine

Gemcitabine impurity A European Pharmacopoeia (EP) Reference Standard

Y0000676

Gemcitabine impurity A

Cytosine Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1350

Cytosine

Isocytosine ≥99%

Sigma-Aldrich

I2127

Isocytosine

biological source

synthetic (organic)

biological source

-

biological source

-

biological source

synthetic (organic)

assay

≥99%

assay

-

assay

-

assay

≥99%

form

powder

form

-

form

-

form

powder

mp

>300 °C (lit.)

mp

>300 °C (lit.)

mp

>300 °C (lit.)

mp

-

solubility

0.5 M HCl: 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow

solubility

-

solubility

-

solubility

acetic acid: 50 mg/mL, clear, colorless

Quality Level

200

Quality Level

-

Quality Level

300

Quality Level

200

Aplicação

Cytosine has been used:
  • for the preparation of nucleobase solutions
  • as a standard for high-performance liquid chromatography (HPLC)
  • for the estimation of global methylation rate
  • for nucleoside 5′-triphosphate (NTP) synthesis
  • purification

Ações bioquímicas/fisiológicas

Cytosine (C) is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA).
Cytosine is a pyrimidine, which forms three hydrogen bonds to base pair with guanine. It forms a nucleotide cytidine, that is phosphorylated to cytidine 5′ monophosphate (CMP), cytidine 5′ diphosphate (CDP) and cytidine 5′ triphosphate (CTP).

Código de classe de armazenamento

11 - Combustible Solids

WGK

WGK 1

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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