Merck
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C9301

Sigma-Aldrich

Collagen from chicken sternal cartilage

Type II (Miller), powder, BioReagent, suitable for cell culture

Número CAS:
Número EC:
Número MDL:
NACRES:
NA.75

Nível de qualidade

300

fonte biológica

chicken (Sternal cartilage)

esterilidade

non-sterile

tipo

Type II (Miller)

linha de produto

BioReagent

teor

60-80% (biuret)

forma

powder

embalagem

glass bottle of 100 mg
poly bottle of 25 mg
glass bottle of 5 mg

technique(s)

cell culture | mammalian: suitable

cobertura de superfície

6‑10 μg/cm2

solubilidade

acetic acid: 0.5-2.0 mg/mL (Dissolve for several hours at 2-8 °C, occasionally swirling.)

nº de adesão UniProt

enviado em

wet ice

temperatura de armazenamento

2-8°C

Gene Information

chicken ... COL2A1(395069)

Descrição geral

Collagen is made of three polypeptide chains. Type 2 collagen is ubiquitously present in the hyaline cartilage. It is a homotrimer made of three α1 chains. Type 2 collagen is also predominant in nucleus pulposus of the vertebral disc and vitreous body of the eye. The proteoglycan obtained from the chicken sternal cartilage is similar to type nine collagen structure.
Collagen is classified into a number of structurally and genetically distinct types. We use the nomenclature proposed by Bornstein and Traub. Do not confuse Sigma type designations with recognized collagen classification types.

Aplicação

Collagen from chicken sternal cartilage has been used in enzyme–linked immunosorbent assay (ELISA) , chondrocyte-mediated tissue production in vitro, induction, treatment and assessment of collagenα induced arthritis (CIA) and cell proliferation assay.

Embalagem

25 mg in poly bottle
5 mg in glass bottle
100 mg in glass bottle

Outras notas

Major component of articular cartilage.

Nota de preparo

Prepared by a modification of the method of Trentham, D.E., et al.

Código de classe de armazenamento

11 - Combustible Solids

WGK

WGK 1

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificado de análise

Insira o número de lote para pesquisar o Certificado de análise (COA).

Certificado de origem

Insira o número de lote para pesquisar o Certificado de origem (COO).

Product Information Sheet

Quotes and Ordering

High-density lipoproteins attenuate high glucose-impaired endothelial cell signaling and functions: potential implications for improved vascular repair in diabetes.
Chen X, et al.
Cardiovascular Diabetology, 16(1), 121-121 (2017)
Blockade of the interleukin?7 receptor inhibits collagen?induced arthritis and is associated with reduction of T cell activity and proinflammatory mediators.
Hartgring S A, et al.
Arthritis and Rheumatism, 62(9), 2716-2725 (2010)
Deletion of either CD55 or CD97 ameliorates arthritis in mouse models.
Hoek R M, et al.
Arthritis and Rheumatism, 62(4), 1036-1042 (2010)
Clinical Impact of Bone and Connective Tissue Markers (2012)
Lipopolysaccharide Increases the Incidence of Collagen?Induced Arthritis in Mice Through Induction of Protease HTRA?1 Expression.
Hou Y, et al.
Arthritis and Rheumatism, 65(11), 2835-2846 (2013)

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