Merck
  • C9993
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C9993

Sigma-Aldrich

Anti-CD9 antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

Synonym(s):
Anti-BA2, Anti-BTCC-1, Anti-DRAP-27, Anti-GIG2, Anti-Growth-inhibiting gene 2 protein, Anti-Leukocyte antigen MIC3, Anti-MRP-1, Anti-Motility related protein, Anti-TSPAN29, Anti-p24 antigen
Número MDL:
NACRES:
NA.41

fonte biológica

rabbit

Nível de qualidade

conjugado

unconjugated

forma do anticorpo

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

forma

buffered aqueous solution

peso molecular

antigen ~25 kDa

species reactivity

human, mouse, rat

concentração

~1 mg/mL

technique(s)

immunohistochemistry: 1:100-1:250
western blot: 1:500-1:1,000

nº de adesão UniProt

enviado em

dry ice

temperatura de armazenamento

−20°C

Gene Information

human ... CD9(928)
mouse ... Cd9(12527)
rat ... Cd9(24936)

Descrição geral

CD9 is a glioma stem cell (GSC)-enriched protein, which belongs to tetraspanin family. It is a cell motility related molecule. The gene is located on human chromosome 12p13.31. CD9 is expressed on pre-B cells, activated T cells and Schwann cells.

Imunogênio

synthetic peptide corresponding to residues 36-50 of human CD9.

Aplicação

Anti-CD9 antibody produced in rabbit has been used in
  • immunostaining
  • identification of hypoxia-induced mesenchymal stem cells (MSC-MVs)
Anti-CD9 antibody produced in rabbit is suitable for immunohistochemistry at a working dilution of 1:100-1:250 and western blotting at a working dilution of 1:500-1:1000. It was used as a primary antibody for the immunolocalization of adhesion protein CD9 during a study to investigate the impact of adhesion proteins on skeletal myoblast differentiation.

Embalagem

100 μg

Ações bioquímicas/fisiológicas

CD9 plays a major role in sperm-egg fusion in fertilization. It enhances cancer invasion and tumor growth in cervical cancer, gastric cancer and glioblastoma (GBM). CD9 is involved in cell invasion, apoptosis and resistance to chemotherapy.

Descrição-alvo

The CD9 protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It can modulate cell adhesion and migration. It also triggers platelet activation and aggregation. In addition, the protein appears to promote muscle cell fusion and support myotube maintenance.

forma física

solution in phosphate buffered saline, containing 0.02% sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de classe de armazenamento

12 - Non Combustible Liquids

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificate of Analysis

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Certificate of Origin

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