Merck
All Photos(5)

D4902

Sigma-Aldrich

Dexamethasone

powder, BioReagent, suitable for cell culture, ≥97%

Synonym(s):
(11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, 9α-Fluoro-16α-methylprednisolone, Prednisolone F
Empirical Formula (Hill Notation):
C22H29FO5
CAS Number:
Molecular Weight:
392.46
Beilstein:
2066651
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.75

fonte biológica

synthetic

Nível de qualidade

linha de produto

BioReagent

teor

≥97%

forma

powder

potência

4-500 ng/mL

technique(s)

cell culture | mammalian: suitable
single cell analysis: suitable

pf

262-264 °C (lit.)

solubilidade

methanol: 25 mg/mL

enviado em

ambient

temperatura de armazenamento

2-8°C

SMILES string

C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO

InChI

1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1

InChI key

UREBDLICKHMUKA-CXSFZGCWSA-N

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This Item
31375PHR152646165
Dexamethasone powder, BioReagent, suitable for cell culture, ≥97%

Sigma-Aldrich

D4902

Dexamethasone

Dexamethasone tested according to Ph. Eur.

Sigma-Aldrich

31375

Dexamethasone

Dexamethasone Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1526

Dexamethasone

Dexamethasone VETRANAL®, analytical standard

Supelco

46165

Dexamethasone

biological source

synthetic

biological source

-

biological source

synthetic

biological source

-

product line

BioReagent

product line

-

product line

-

product line

VETRANAL®

assay

≥97%

assay

99.6%

assay

-

assay

-

form

powder

form

solid

form

-

form

-

potency

4-500 ng/mL

potency

-

potency

-

potency

-

technique(s)

cell culture | mammalian: suitable, single cell analysis: suitable

technique(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

Aplicação

Dexamethasone is used to study apoptosis, cell signaling pathways, cell differentiation and gene expression.

Ações bioquímicas/fisiológicas

Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.
It is poorly metabolized in the body and has great affinity and bioavailability.

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

forma física

powder 2-8 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw

Reconstituição

To prepare 20 μg/ml stock solution, add 1ml absolute ethanol per mg product; gently swirl to dissolve. Add 49 ml sterile medium per ml of ethanol added, while mixing, to acheive final concentration of 20 μg/ml.

Pictogramas

Health hazard

Palavra indicadora

Danger

Frases de perigo

Classificações de perigo

Repr. 1B

Código de classe de armazenamento

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

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