Merck
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F5006

Sigma-Aldrich

2-Fluoro-2-deoxy-D-glucose

glycosylation inhibitor, glucose analog

Synonym(s):
2-Deoxy-2-fluoro-D-glucose, FDG, 2-Deoxy-2-fluoro-D-glucose
Empirical Formula (Hill Notation):
C6H11FO5
CAS Number:
Molecular Weight:
182.15
Número MDL:
ID de substância PubChem:

Nível de qualidade

300

temperatura de armazenamento

2-8°C

SMILES string

OCC1OC(O)C(F)C(O)C1O

InChI

1S/C6H11FO5/c7-3-5(10)4(9)2(1-8)12-6(3)11/h2-6,8-11H,1H2

InChI key

ZCXUVYAZINUVJD-UHFFFAOYSA-N

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Descrição geral

2-Fluoro-2-deoxy-D-glucose, also known as F-18 FDG, is non-toxic and a structural analog of glucose, significantly inhibiting glycosylation. As a glucose analog, uptake of 2-Fluoro-2-deoxy-D-glucose is rapid in brain and heart cells. 2-Fluoro-2-deoxy-D-glucose is a Natural isotope form of 18F-FDG that can be taken up by cells but does not undergo metabolic glycolysis.

Aplicação

2-Fluoro-2-deoxy-D-glucose is used as a tracer for rapid tumor detection. It is used as a glucose analog to study glucose uptake in mice with radiation and burn injuries. Oncology therapy studies use FDG in combination with PET (Positron Emission Topography)

Embalagem

25 mg in poly bottle
100 mg in glass bottle

Ações bioquímicas/fisiológicas

Glucose analog that inhibits cellular glycosylation. Natural isotope-form of 18F-FDG that can be taken up by cells but does not undergo metabolic glycolysis.

Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Classificações de perigo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

WGK

WGK 3

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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