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F7879

Sigma-Aldrich

Ferritin, cationized from horse spleen

10 mg/mL in 0.15 M NaCl

Número CAS:
Número MDL:
NACRES:
NA.26

Nível de qualidade

200

fonte biológica

horse spleen

esterilidade

sterile-filtered

forma

liquid

concentração

10 mg/mL in 0.15 M NaCl

aplicação(ões)

cell culture | mammalian: suitable
electron microscopy: suitable

nº de adesão UniProt

temperatura de armazenamento

2-8°C

Gene Information

horse ... FTL(100051593)

Descrição geral

Ferritin, an iron-storage protein is usually present in the liver and spleen in mammals. Iron and ferritin are distributed relatively same in the eye. Ferritin is made up of heavy and light chains.

Aplicação

Ferritin, cationized from horse spleen has been used:
  • to incubate amoebae (106) in the study, to determine whether trophozoites are able to take up ferritin and internalise this protein for their growth in axenic culture
  • to determine phagosome-lysosome fusion by electron microscopy
  • to label freshly excised chick optic tecta in serum free incubation medium

Ferritin is an iron storage protein that plays a central role in iron metabolism, and may be elevated in inflammatory or malignant diseases. It has been used in studies as an indicator of body iron supply, but may prove inaccurate in in the presence of chronic inflammation.
A cationic derivative used to label negatively charged cell membranes for visualization by electron microscopy.

Ações bioquímicas/fisiológicas

Ferritin holds iron at its ferric state (Fe3+). The core of ferritin has the capability to hold 4500 iron molecules. It is essential to store iron in vertebrates. Ferritin is also essential to store and transport iron in invertebrates. It plays a key role in dietary iron absorption.

Nota de preparo

Prepared by coupling horse spleen ferritin with N,N-dimethyl-1,3-propanediamine (DMPA).

Storage Class Code

12 - Non Combustible Liquids

WGK Alemanha

WGK 2

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Certificado de análise

Certificado de origem

Fabrizio Bardelli et al.
Scientific reports, 7, 44862-44862 (2017-03-24)
Once penetrated into the lungs of exposed people, asbestos induces an in vivo biomineralisation process that leads to the formation of a ferruginous coating embedding the fibres. The ensemble of the fibre and the coating is referred to as asbestos...
Recycling of plasmalemma in chick tectal growth cones
Cheng, TP and Reese, TS
The Journal of Neuroscience, 7(6), 1752-1759 (1987)
Maria Jose Uria et al.
The Journal of experimental medicine, 205(6), 1423-1434 (2008-05-28)
The presence of serum bactericidal antibodies is a proven correlate of protection against systemic infection with the important human pathogen Neisseria meningitidis. We have identified three serogroup C N. meningitidis (MenC) isolates recovered from patients with invasive meningococcal disease that...
Iron-Induced Retinal Damage
Handbook of nutrition, diet, and the eye, 619-626 (2014)
Use of cationized ferritin as a label of negative charges on cell surfaces.
D Danon et al.
Journal of ultrastructure research, 38(5), 500-510 (1972-03-01)

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