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G5013

Sigma-Aldrich

G 418 disulfate salt

potency: ≥720 μg per mg (dried basis)

Sinônimo(s):
Antibiotic G418
Empirical Formula (Hill Notation):
C20H40N4O10 · 2H2SO4
Número CAS:
Peso molecular:
692.71
Número MDL:
ID de substância PubChem:
NACRES:
NA.85

forma

powder

Nível de qualidade

200

potência

≥720 μg per mg (dried basis)

cor

white to off-white

solubilidade

H2O: 100 mg/mL

Modo de ação

protein synthesis | interferes

espectro de atividade do antibiótico

Gram-negative bacteria

temperatura de armazenamento

2-8°C

SMILES string

OS(O)(=O)=O.OS(O)(=O)=O.CN[C@H]1[C@H](O)[C@@H](OC[C@@]1(C)O)O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H]([C@H](C)O)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O

InChI

1S/C20H40N4O10.2H2O4S/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19;2*1-5(2,3)4/h6-19,24-30H,4-5,21-23H2,1-3H3;2*(H2,1,2,3,4)/t6?,7-,8+,9+,10+,11-,12-,13-,14+,15+,16-,17-,18+,19-,20+;;/m0../s1

InChI key

UHEPSJJJMTWUCP-NKCAIAFTSA-N

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Descrição geral

Chemical structure: aminoglycoside

Embalagem

250 mg in glass bottle
1, 5 g in glass bottle

Atenção

The product is stable for three years when stored at 2-8°C. Aqueous solutions stored frozen at -20 to -70 °C should be stable for approximately six months.

Nota de preparo

G418 powder is soluble in water at 100 mg/mL.

Pictogramas

Health hazard

Palavra indicadora

Danger

Frases de perigo

Classificações de perigo

Resp. Sens. 1 - Skin Sens. 1

Código de classe de armazenamento

13 - Non Combustible Solids

WGK

WGK 3

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificado de análise

Certificado de origem

Triplet imaging of oxygen consumption during the contraction of a single smooth muscle cell (A7r5).
Matthias Geissbuehler et al.
Advances in experimental medicine and biology, 737, 263-268 (2012-01-20)
Yoshie Tange et al.
PLoS genetics, 8(6), e1002776-e1002776 (2012-06-28)
To identify the genes required to sustain aneuploid viability, we screened a deletion library of non-essential genes in the fission yeast Schizosaccharomyces pombe, in which most types of aneuploidy are eventually lethal to the cell. Aneuploids remain viable for a
null
Shijia Yu et al.
Frontiers in cellular neuroscience, 14, 193-193 (2020-08-08)
Cerebral ischemic stroke is regarded as one of the most serious diseases in the human central nervous system. The secondary ischemia and reperfusion (I/R) injury increased the difficulty of treatment. Moreover, the latent molecular regulating mechanism in I/R injury is
Frida C Mohlin et al.
Molecular immunology, 65(2), 367-376 (2015-03-04)
Atypical hemolytic uremic syndrome (aHUS) is a disease of complement dysregulation, characterized by hemolytic anemia, thrombocytopenia and acute renal failure. Mutations in complement inhibitors are major risk factors for development of aHUS. The three aHUS patients reported in this study

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