Todas as fotos(2)

G5146

Sigma-Aldrich

D-(+)-Glucose

Hybri-Max, powder, BioReagent, suitable for hybridoma

Sinônimo(s):
Dextrose
Empirical Formula (Hill Notation):
C6H12O6
Número CAS:
Peso molecular:
180.16
Beilstein:
1724615
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.75

Nível de qualidade

200

fonte biológica

maize

grau

Hybri-Max

linha de produto

BioReagent

teor

≥99.5%

forma

powder

technique(s)

cell culture | hybridoma: suitable

Impurezas

endotoxin, tested

pf

150-152 °C (lit.)

solubilidade

H2O: 2g + 15 mL, clear, colorless

SMILES string

OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1

InChI key

WQZGKKKJIJFFOK-DVKNGEFBSA-N

Gene Information

human ... PYGM(5837)

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Categorias relacionadas

Descrição geral

Glycogen phosphorylase (PYG) exists as brain and muscle isoform. It is expressed in astrocytes and neurons respectively. The PYGM gene is mapped to human chromosome 11q13.1.

Aplicação

D-(+)-Glucose has been used in cell engineering. It has also been used to perform oral glucose tolerance test.

Embalagem

1 kg in poly bottle
10 kg in poly drum

Ações bioquímicas/fisiológicas

Glycogen phosphorylase, muscle associated (PYGM), is an important contributor to glycogenolysis. Down regulation of PYGM gene is observed in schizophrenia. Mutation in PYGM leads to McArdle disease, a glycogen storage disorder. The PYGM gene is significantly associated with energy production.

Informações legais

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Código de classe de armazenamento

11 - Combustible Solids

WGK

WGK 1

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificado de análise

Certificado de origem

Comparative metabolic analysis of CHO cell clones obtained through cell engineering, for IgG productivity, growth and cell longevity
Wilkens CA and Gerdtzen ZP
PLoS ONE, 10(3) (2015)
Electrical vs manual acupuncture stimulation in a rat model of polycystic ovary syndrome: different effects on muscle and fat tissue insulin signaling
Johansson J, et al.
PLoS ONE, 8(1) (2013)
Genetic evaluation of AMPD1, CPT2, and PGYM metabolic enzymes in patients with chronic fatigue syndrome
Maltese PE, et al.
Genetics and molecular research : GMR, 15(3), 1-10 (2016)
Novel variant in the PYGM gene causing late-onset limb-girdle myopathy, ptosis, and camptocormia
Cheraud C, et al.
Muscle and Nerve, 57(1), 157-160 (2018)
The glial phosphorylase of glycogen isoform is reduced in the dorsolateral prefrontal cortex in chronic schizophrenia
Pinacho R, et al.
Schizophrenia Research, 177(1-3), 37-43 (2016)

Artigos

Aerobic Glycolysis and the Warburg Effect

We presents an article about the Warburg effect, and how it is the enhanced conversion of glucose to lactate observed in tumor cells, even in the presence of normal levels of oxygen. Otto Heinrich Warburg demonstrated in 1924 that cancer cells show an increased dependence on glycolysis to meet their energy needs, regardless of whether they were well-oxygenated or not.

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