Merck
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G7126

Sigma-Aldrich

Glycine

ReagentPlus®, ≥99% (HPLC)

Sinônimo(s):
Aminoacetic acid, Aminoethanoic acid, Glycocoll
Fórmula linear:
NH2CH2COOH
Número CAS:
Peso molecular:
75.07
Beilstein:
635782
Número EC:
Número MDL:
eCl@ss:
32160406
ID de substância PubChem:
NACRES:
NA.26

Nível de qualidade

200

linha de produto

ReagentPlus®

teor

≥99% (HPLC)

forma

powder

technique(s)

western blot: suitable

Impurezas

≤0.01% Ammonia

perda

≤0.2% loss on drying

cor

white to off-white

pKa (25 °C)

(1) 2.35, (2) 9.60
2.35

pf

240 °C (dec.) (lit.)

solubilidade

H2O: 200 mg/mL, clear, colorless to faintly yellow

SMILES string

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

Gene Information

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Categorias relacionadas

Descrição geral

Glycine is a non-chiral amino acid. Glycine is a molecule with pI of 6.7, which is similar to the pH of stacking region in polyacrylamide gels. It has advantage of low mobility, hydrophobicity and it does not associate with proteins.

Aplicação

  • Glycine has been added in the transfer buffer during western blotting procedure.
  • It has been used in the solution prepared for dissolving formazan crystals in the MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyltetrazolium bromide) cytotoxicity assay.
  • It has been used for terminating the rat basophilic leukemia (RBL) assay.

Embalagem

5, 25 kg in poly drum
10 mg in glass bottle
1 kg in poly bottle
100, 500 g in poly bottle

Ações bioquímicas/fisiológicas

Glycine is an inhibitory neurotransmitter in the central nervous system and works as an allosteric regulator of NMDA (N-methyl-D-aspartate) receptors. It is involved in processing of motor and sensory data, thereby regulating movement, vision and audition.
Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Informações legais

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Código de classe de armazenamento

11 - Combustible Solids

WGK

WGK 1

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificado de análise

Insira o número de lote para pesquisar o Certificado de análise (COA).

Certificado de origem

Insira o número de lote para pesquisar o Certificado de origem (COO).

Assessment of the sensitizing potential of processed peanut proteins in Brown Norway rats: roasting does not enhance allergenicity.
Kroghsbo S et al.
PLoS ONE, 9, e96475-e96475 (2014)
A functional study on the migration of human monocytes to human leukemic cell lines and the role of monocyte chemoattractant protein-1.
Legdeur MC et al.
Leukemia, 11, 1904-1904 (1997)
Formalin-inactivated bovine RSV vaccine enhances a Th2 mediated immune response in infected cattle.
Kalina WV et al.
Vaccine, 22, 1465-1465 (2004)
Westermeier R
Electrophoresis in Practice: A Guide to Methods and Applications of DNA and Protein Separations (2016)
Amino Acids, Peptides and Proteins in Organic Chemistry (2013)

Artigos

Nucleotide Synthesis in Cancer Cells

Neoplastic cells are highly dependent on the de novo synthesis of nucleotides to maintain sufficient pools to support DNA replication and the production of RNA.

Protocolos

Enzymatic Assay of Phytase (EC 3.1.3.8)

Derived from procedure SSPHYT02. Includes template updates to current SOP specifications and incorporation of notes into the procedure.

Enzymatic Assay and ATP Sensitivity Test of Luciferase

Objective: To standardize a procedure to determine the enzymatic activity of Luciferase and/or to determine the ATP detection limit of Luciferase.

Enzymatic Assay of 5’-Nucleotidase

Objective: To standardize a procedure for determining the enzymatic activity of 5’-Nucleotidase.

Enzymatic Assay of β-Glucuronidase (EC 3.2.1.31) from E. coli

Objective: To standardize a procedure for the enzymatic assay of β-Glucuronidase.

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