Merck
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G7126

Sigma-Aldrich

Glicina

ReagentPlus®, ≥99% (HPLC)

Synonym(s):
Glicocol, Ácido aminoacético, Ácido aminoetanoico
Linear Formula:
NH2CH2COOH
CAS Number:
Molecular Weight:
75.07
Beilstein:
635782
Número EC:
Número MDL:
eCl@ss:
32160406
ID de substância PubChem:
NACRES:
NA.26

Nível de qualidade

linha de produto

ReagentPlus®

Ensaio

≥99% (HPLC)

forma

powder

technique(s)

western blot: suitable

Impurezas

≤0.01% Ammonia

perda

≤0.2% loss on drying

cor

white to off-white

pKa (25 °C)

(1) 2.35, (2) 9.60
2.35

pf

240 °C (dec.) (lit.)

solubilidade

H2O: 200 mg/mL, clear, colorless to faintly yellow

SMILES string

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

Gene Information

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Sigma-Aldrich

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SAFC

1.03669

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Glycine ACS reagent, ≥98.5%

Sigma-Aldrich

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Glycine

product line

ReagentPlus®

product line

-

product line

EMPROVE® EXPERT

product line

-

assay

≥99% (HPLC)

assay

≥99%

assay

99.0-101.0% (calculated on dried substance, perchloric acid titration)

assay

≥98.5%

form

powder

form

powder

form

granular

form

crystals, powder or granules

technique(s)

western blot: suitable

technique(s)

electrophoresis: suitable, western blot: suitable

technique(s)

inhibition assay: suitable

technique(s)

-

impurities

≤0.01% Ammonia

impurities

≤0.01% Insoluble matter

impurities

-

impurities

H2SO4, passes test (darkened), Hydrolyzable subsances, passes test

color

white to off-white

color

white to off-white

color

-

color

-

Descrição geral

A glicina é um aminoácido não quiral. A glicina é uma molécula com pI de 6,7, que é semelhante ao pH da região de empilhamento em géis de poliacrilamida. Tem a vantagem de ter baixa mobilidade, hidrofobicidade e não se associar a proteínas.

Aplicação

  • A glicina foi adicionada ao tampão de transferência durante o procedimento de western blotting.
  • Ela foi usada na solução preparada para dissolver cristais de formazan em ensaio de citotoxicidade com MTT (brometo de 3-[4,5-dimetiltiazol-2-il]-2,5 difeniltetrazólio).
  • Ela foi usada para encerrar o ensaio de leucemia basofílica de rato (RBL).

Ações bioquímicas/fisiológicas

A glicina é um neurotransmissor inibitório no sistema nervoso central e funciona como um regulador alostérico de receptores de NMDA (N-metil-D-aspartato). Está envolvida no processamento de dados motores e sensoriais, regulando, portanto, movimento, visão e audição.
Neurotransmissor inibitório na coluna vertebral, regulador alostérico dos receptores de NMDA.

Informações legais

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Código de classe de armazenamento

11 - Combustible Solids

WGK

WGK 1

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


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