Merck
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G8769

Sigma-Aldrich

D-(+)-Glucose solution

45% in H2O, sterile-filtered, BioXtra, suitable for cell culture

Sinônimo(s):
D-Glucopyranose
Empirical Formula (Hill Notation):
C6H12O6
Número CAS:
Peso molecular:
180.16
Beilstein:
1281608
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.75

Nível de qualidade

200

esterilidade

sterile-filtered

linha de produto

BioXtra

forma

solution

concentração

45% in H2O

technique(s)

cell culture | mammalian: suitable

Impurezas

endotoxin, tested

SMILES string

OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1

InChI key

WQZGKKKJIJFFOK-DVKNGEFBSA-N

Gene Information

human ... PYGM(5837)

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Descrição geral

Glucose is the energy currency essential for physiological processes in the living cells. It serves as a precursor for glycoproteins, glycolipids and glycosaminoglycans.

Aplicação

D-(+)-Glucose solution has been used as a medium supplement:
  • in Dulbecco′s Modified Eagle Medium (DMEM) for culturing Flp-In  293 cells
  • in dissection medium for coronal slices from rat brain
  • in neurobasal medium for culturing hippocampi cells

Provides the primary energy source for cell metabolism.

Ações bioquímicas/fisiológicas

Glucose is a crucial component for the growth and maintenance of mammalian cells in in vitro conditions and is essential for productivity and quality. Its high metabolic turnover favors osteoclast differentiation. The levels of glucose modulate the migration and growth of tumor cells. HeLa cells display high mobility at low glucose levels.

Código de classe de armazenamento

10 - Combustible liquids

WGK

WGK 1

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Certificado de análise

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Certificado de origem

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Glucose: an energy currency and structural precursor in articular cartilage and bone with emerging roles as an extracellular signaling molecule and metabolic regulator
Mobasheri A
Frontiers in Endocrinology, 3, 153-153 (2012)
High glucose and low specific cell growth but not mild hypothermia improve specific r-protein productivity in chemostat culture of CHO cells
Vergara M, et al.
Testing, 13(8), e0202098-e0202098 (2018)
Investigation of the Influence of Glucose Concentration on Cancer Cells by Using a Microfluidic Gradient Generator without the Induction of Large Shear Stress
Ishida T, et al.
Micromachines, 7(9), 155-155 (2016)
Chad A Dumstorf et al.
Molecular cancer therapeutics, 9(12), 3158-3163 (2010-10-26)
Enzastaurin (LY317615.HCl) is currently in a phase III registration trial for diffuse large B-Cell lymphoma and numerous phase II clinical trials. Enzastaurin suppresses angiogenesis and induces apoptosis in multiple human tumor cell lines by inhibiting protein kinase C (PKC) and
An ex vivo method for evaluating the biocompatibility of neural electrodes in rat brain slice cultures
Koeneman BA, et al.
Journal of Neuroscience Methods, 137(2), 257-263 (2004)

Artigos

Insulin Signaling and Energy Homeostasis

Glucose metabolism is regulated by the opposing actions of insulin and glucagon. Insulin is released from pancreatic ß cells in response to high blood glucose levels and regulates glucose metabolism through its actions on muscle, liver, and adipose tissue.

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