I0908

All Photos(1)

I0908

Insulina

meets USP testing specifications

All Photos(1)

Synonym(s):

Human insulin

Empirical Formula (Hill Notation):

C₂₅₇H₃₈₃N₆₅O₇₇S₆

CAS Number:

11061-68-0

Molecular Weight:

5807.57

Número EC:

234-279-7

Número MDL:

MFCD00131380

NACRES:

NA.21

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USP

1342059

Insulin glargine

Y0000349

Insulin aspart

Y0001544

Insulin glargine for peak identification

USP

1342300

Insulin (Pork)

Y0001717

Insulin porcine for system suitability

Sigma-Aldrich

L6661

Lactic acid

Supelco

PHR8925

Human Insulin

Sigma-Aldrich

N6160

Novobiocin sodium

fonte biológica

human

Nível de qualidade

200

recombinante

expressed in Saccharomyces cerevisiae

Agency

meets USP testing specifications

forma

solid

potência

≥27.5 units/mg (dry)

technique(s)

cell culture | mammalian: suitable

nº de adesão UniProt

P01308

application(s)

pharmaceutical (small molecule)

temperatura de armazenamento

−20°C

InChI key

PBGKTOXHQIOBKM-FHFVDXKLSA-N

Gene Information

human ... INS(3630)

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This Item	PHR8925	I1507	I2643
Sigma-Aldrich I0908 Insulin human	Supelco PHR8925 Human Insulin	Sigma-Aldrich I1507 Insulin human	Sigma-Aldrich I2643 Insulin human
biological source human	biological source -	biological source semisynthetic	biological source human
recombinant expressed in Saccharomyces cerevisiae	recombinant -	recombinant -	recombinant expressed in yeast (proprietary host)
form solid	form -	form powder	form powder
potency ≥27.5 units/mg (dry)	potency -	potency -	potency ≥27.5 units/mg (dried basis)
technique(s) cell culture \| mammalian: suitable	technique(s) -	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable
UniProt accession no. P01308	UniProt accession no. -	UniProt accession no. P01308	UniProt accession no. P01308

Ações bioquímicas/fisiológicas

Hormônio polipeptídico de duas cadeias produzido pelas células β das ilhotas pancreáticas. Seu peso molecular é de cerca de 5800 Da. As cadeias α e β são ligadas por duas pontes dissulfeto entre as cadeias. A cadeia α contém uma ponte dissulfeto dentro da cadeia. A insulina regula a captação celular, o uso e o armazenamento de glicose, aminoácidos e ácidos graxos, além de inibir a quebra de glicogênio, proteínas e gordura.

Outras notas

InChI: 1S/C257H383N65O77S6/c1-29-131(23)205(313-193(339)104-259)252(393)317-204(130(21)22)248(389)288-159(75-82-200(349)350)217(358)282-156(71-78-189(263)335)221(362)308-183-116-403-404-117-184-243(384)305-178(111-324)240(381)294-162(88-123(7)8)225(366)295-168(95-140-53-61-146(329)62-54-140)228(369)283-154(69-76-187(261)333)218(359)290-161(87-122(5)6)223(364)285-158(74-81-199(347)348)220(361)302-174(101-190(264)336)235(376)298-170(97-142-57-65-148(331)66-58-142)231(372)309-182(242(383)304-176(255(396)397)103-192(266)338)115-402-401-114-181(214(355)273-107-194(340)278-153(72-79-197(343)344)216(357)281-151(51-42-84-271-257(267)268)212(353)272-108-195(341)279-166(93-138-46-36-32-37-47-138)227(368)297-167(94-139-48-38-33-39-49-139)230(371)299-171(98-143-59-67-149(332)68-60-143)238(379)320-208(135(27)327)254(395)322-85-43-52-186(322)246(387)286-152(50-40-41-83-258)222(363)321-209(136(28)328)256(398)399)311-250(391)203(129(19)20)316-236(377)164(90-125(11)12)292-229(370)169(96-141-55-63-147(330)64-56-141)296-224(365)160(86-121(3)4)289-210(351)133(25)277-215(356)157(73-80-198(345)346)287-247(388)202(128(17)18)315-237(378)165(91-126(13)14)293-233(374)173(100-145-106-270-120-276-145)301-239(380)177(110-323)280-196(342)109-274-213(354)180(113-400-405-118-185(310-244(183)385)245(386)319-207(134(26)326)253(394)306-179(112-325)241(382)318-206(132(24)30-2)251(392)312-184)307-226(367)163(89-124(9)10)291-232(373)172(99-144-105-269-119-275-144)300-219(360)155(70-77-188(262)334)284-234(375)175(102-191(265)337)303-249(390)201(127(15)16)314-211(352)150(260)92-137-44-34-31-35-45-137/h31-39,44-49,53-68,105-106,119-136,150-186,201-209,323-332H,29-30,40-43,50-52,69-104,107-118,258-260H2,1-28H3,(H2,261,333)(H2,262,334)(H2,263,335)(H2,264,336)(H2,265,337)(H2,266,338)(H,269,275)(H,270,276)(H,272,353)(H,273,355)(H,274,354)(H,277,356)(H,278,340)(H,279,341)(H,280,342)(H,281,357)(H,282,358)(H,283,369)(H,284,375)(H,285,364)(H,286,387)(H,287,388)(H,288,389)(H,289,351)(H,290,359)(H,291,373)(H,292,370)(H,293,374)(H,294,381)(H,295,366)(H,296,365)(H,297,368)(H,298,376)(H,299,371)(H,300,360)(H,301,380)(H,302,361)(H,303,390)(H,304,383)(H,305,384)(H,306,394)(H,307,367)(H,308,362)(H,309,372)(H,310,385)(H,311,391)(H,312,392)(H,313,339)(H,314,352)(H,315,378)(H,316,377)(H,317,393)(H,318,382)(H,319,386)(H,320,379)(H,321,363)(H,343,344)(H,345,346)(H,347,348)(H,349,350)(H,396,397)(H,398,399)(H4,267,268,271)/t131-,132-,133-,134+,135+,136+,150-,151-,152-,153-,154-,155-,156-,157-,158-,159-,160-,161-,162-,163-,164-,165-,166-,167-,168-,169-,170-,171-,172-,173-,174-,175-,176-,177-,178-,179-,180-,181-,182-,183-,184-,185-,186-,201-,202-,203-,204-,205-,206-,207-,208-,209-/m0/s1

Código de classe de armazenamento

11 - Combustible Solids

WGK

nwg

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

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Insulina

meets USP testing specifications

Recommended Products

Properties

fonte biológica

Nível de qualidade

recombinante

Agency

forma

potência

technique(s)

nº de adesão UniProt

application(s)

temperatura de armazenamento

InChI key

Gene Information

Compare Similar Items

This Item

Description

Ações bioquímicas/fisiológicas

Outras notas

Safety Information

Código de classe de armazenamento

WGK

Ponto de fulgor (ºF)

Ponto de fulgor (ºC)

Equipamento de proteção individual

Documentation

Certificates of Analysis (COA)

Already Own This Product?

Difficulty Finding Your Product Or Lot/Batch Number?

Aldrich Products

Not Finding What You Are Looking For?

Technical Service