Merck
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I8885

Sigma-Aldrich

Anti-Human IgG (Fc specific) antibody produced in goat

whole antiserum

Número MDL:
NACRES:
NA.46

fonte biológica

goat

Nível de qualidade

conjugado

unconjugated

forma do anticorpo

whole antiserum

antibody product type

secondary antibodies

clone

polyclonal

contém

15 mM sodium azide

technique(s)

indirect ELISA: 1:50,000
quantitative precipitin assay: 4.0-7.0 mg/mL

enviado em

dry ice

temperatura de armazenamento

−20°C

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Este Item
I9135I1011I9010
conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

antibody form

whole antiserum

antibody form

whole antiserum

antibody form

whole antiserum

antibody form

whole antiserum

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

technique(s)

indirect ELISA: 1:50,000, quantitative precipitin assay: 4.0-7.0 mg/mL

technique(s)

indirect ELISA: 1:100,000, quantitative precipitin assay: 1.5 mg/mL

technique(s)

indirect ELISA: 1:40,000, quantitative precipitin assay: 4.0 mg/mL

technique(s)

indirect ELISA: 1:30,000, quantitative precipitin assay: 4.0 mg/mL

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

Descrição geral

Immunoglobulin G (IgG), a widely expressed serum antibody, has two heavy chains and two light chains connected by a disulfide bond. It is a glycoprotein, usually found as a monomer. IgG is further subdivided into four classes namely, IgG1, IgG2, IgG3, and IgG4. IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. About 70 % of the total immunoglobulin consists of IgG.

Especificidade

Specificity for the Fc fragment of human IgG is determined by immunoelectrophoresis (IEP) versus normal human serum and Fc fragment of human IgG. No reactivity is observed versus purified human IgA, IgG (Fab fragment), IgM, Bence Jones kappa and Bence Jones lambda myeloma proteins.

Aplicação

Anti-Human IgG (Fc specific) antibody produced in goat has been used in enzyme-linked immunosorbent assay (ELISA).

Ações bioquímicas/fisiológicas

Immunoglobulin G (IgG) mainly helps in immune defense. It participates in hypersensitivity type II and type III. It provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.

forma física

Goat Anti-Human IgG is supplied as a liquid containing 0.1% sodium azide (see MSDS) as a preservative.

Armazenamento e estabilidade

For continuous use, store at 2-8°C for up to one month. For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in "frost-free" freezers is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. This goat antiserum was maintained at pH 5.0 for 40 minutes to meet U.S.D.A. requirements.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de classe de armazenamento

10 - Combustible liquids

WGK

WGK 1


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Specific IgG for cat allergens in patients with allergic conjunctivitis
<BIG><BIG>Miyama A, et al</BIG></BIG>
International Ophthalmology, 35, 575-586 (2015)
Thomas McDonnell et al.
Frontiers in immunology, 9, 2244-2244 (2018-10-17)
Antiphospholipid antibodies (aPL), the serological hallmark of antiphospholipid syndrome (APS), are a heterogeneous group of autoantibodies raised against circulating blood proteins. Of these proteins, the phospholipid-binding b2-glycoprotein I (β2GPI) is considered to be the main autoantigen in APS. Indeed, IgG
Li-Ping Liu et al.
Cells, 11(1) (2022-01-12)
Amniotic epithelial stem cells (AESCs) are considered as potential alternatives to keratinocytes (KCs) in tissue-engineered skin substitutes used for treating skin damage. However, their clinical application is limited since similarities and distinctions between AESCs and KCs remain unclear. Herein, a
S Hashira et al.
Pediatrics international : official journal of the Japan Pediatric Society, 42(4), 337-342 (2000-09-15)
Maternal immunoglobulin G (IgG), transferred across the placenta to the fetus during intrauterine life, is an important component of the neonatal immunological defence mechanisms against infection. There is controversy with respect to differences in placental transfer of the different IgG

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