Merck
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I9010

Sigma-Aldrich

Anti-Human IgG (Fab specific) antibody produced in goat

whole antiserum

Número MDL:
NACRES:
NA.46

fonte biológica

goat

conjugado

unconjugated

forma do anticorpo

whole antiserum

antibody product type

secondary antibodies

clone

polyclonal

contém

15 mM sodium azide

technique(s)

indirect ELISA: 1:30,000
quantitative precipitin assay: 4.0 mg/mL

enviado em

dry ice

temperatura de armazenamento

−20°C

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Este Item
I1136I9135I1011
conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

antibody form

whole antiserum

antibody form

whole antiserum

antibody form

whole antiserum

antibody form

whole antiserum

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

technique(s)

indirect ELISA: 1:30,000, quantitative precipitin assay: 4.0 mg/mL

technique(s)

indirect ELISA: 1:40,000, quantitative precipitin assay: 4.0 mg/mL

technique(s)

indirect ELISA: 1:100,000, quantitative precipitin assay: 1.5 mg/mL

technique(s)

indirect ELISA: 1:40,000, quantitative precipitin assay: 4.0 mg/mL

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

Descrição geral

Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. Immunoglobulins have two heavy chains and two light chains connected by a disulfide bond. It is a glycoprotein. IgG is usually found as a monomer. IgG is further subdivided into four classes namely, IgG1, IgG2, IgG3, and IgG4. About 70 percent of the total immunoglobulin consists of IgG.

Especificidade

Reactivity is observed versus purified human IgA, IgM, Bence Jones Kappa and Bence Jones Lambda myeloma proteins. No reactivity is observed versus Fc fragment of human IgG.

Aplicação

Anti-Human IgG (Fab specific) antibody produced in goat has been used in immunological assays. It has also been used in cellulose substrates as immobilized anti-hIgG to detect human immunoglobulin G (hIgG) from fluid matrices.
Anti-Human IgG (Fab specific) antibody produced in goat was used in capture ELISA at a dilution of 1:10,000.

Ações bioquímicas/fisiológicas

IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.

forma física

Supplied as a liquid containing 15 mM sodium azide as a preservative.

Nota de preparo

delipidized

Armazenamento e estabilidade

For continuous use, store at 2-8 °C for up to one month. For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in "frost-free" freezers not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de classe de armazenamento

10 - Combustible liquids

WGK

WGK 2

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Hannes Orelma et al.
Biomacromolecules, 13(9), 2802-2810 (2012-07-27)
We investigated the adsorption and chemical conjugation of avidin and its deglycosylated form, neutravidin, on films of regenerated and nanofibrillar cellulose. The dynamics and extent of biomolecular attachment were monitored in situ by quartz crystal microbalance microgravimetry and ex situ
Label-free biodetection using capacitive micromachined ultrasonic transducers (CMUTs) and its application for cardiovascular disease diagnostics
Eaimkhong S, et al.
Journal of nanomedicine & nanotechnology, 3(144), 2-2 (2012)
Jane A Potter et al.
Journal of virology, 86(23), 12923-12932 (2012-09-21)
The E2 envelope glycoprotein of hepatitis C virus (HCV) binds to the host entry factor CD81 and is the principal target for neutralizing antibodies (NAbs). Most NAbs recognize hypervariable region 1 on E2, which undergoes frequent mutation, thereby allowing the
Wei Wang et al.
Journal of pharmaceutical sciences, 96(1), 1-26 (2006-09-26)
The number of therapeutic monoclonal antibody in development has increased tremendously over the last several years and this trend continues. At present there are more than 23 approved antibodies on the US market and an estimated 200 or more are
S Hashira et al.
Pediatrics international : official journal of the Japan Pediatric Society, 42(4), 337-342 (2000-09-15)
Maternal immunoglobulin G (IgG), transferred across the placenta to the fetus during intrauterine life, is an important component of the neonatal immunological defence mechanisms against infection. There is controversy with respect to differences in placental transfer of the different IgG

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