L1376

Sigma-Aldrich

Linoleic acid

≥99%

Sinônimo(s):
Telfairic acid, 9-cis,12-cis-Linoleic acid, cis-9,cis-12-Octadecadienoic acid
Fórmula linear:
CH3(CH2)4CH=CHCH2CH=CH(CH2)7CO2H
Número CAS:
Peso molecular:
280.45
Beilstein/REAXYS Number:
1727101
Número EC:
Número MDL:
ID de substância PubChem:

Nível de qualidade

200

fonte biológica

plant oil (safflower)

teor

≥99%

forma

liquid

índice de refração

n20/D 1.466 (lit.)

pb

229-230 °C/16 mmHg (lit.)

pf

−5 °C (lit.)

densidade

0.902 g/mL at 25 °C (lit.)

grupo funcional

carboxylic acid

enviado em

ambient

temperatura de armazenamento

−20°C

SMILES string

OC(CCCCCCC/C=C\C/C=C\CCCCC)=O

InChI

1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/b7-6-,10-9-

InChI key

OYHQOLUKZRVURQ-HZJYTTRNSA-N

Gene Information

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Categorias relacionadas

Embalagem

1, 5, 10, 25 g in ampule
10, 500 mg in ampule

Ações bioquímicas/fisiológicas

Linoleic acid is an n-6 polyunsaturated essential fatty acid (PUFA) used as a precursor of arachidonic acid (AA) and various prostaglandins. Linoleic acid may be used to improve the delivery and efficacy of anticancer drugs and in cancer protection.
Linoleic acid increases cell proliferation and gene expression of PPARα and its target genes such as acyl-CoA oxidase in primary duck hepatocytes .

storage_class_code

10 - Combustible liquids

WGK Alemanha

WGK 1

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves

Certificado de análise

Certificado de origem

Allison Dilzer et al.
Critical reviews in food science and nutrition, 52(6), 488-513 (2012-03-29)
Conjugated linoleic acid (CLA) has drawn significant attention in the last two decades for its variety of biologically beneficial effects. CLA reduces body fat, cardiovascular diseases and cancer, and modulates immune and inflammatory responses as well as improves bone mass....
Céline Robo et al.
Acta biomaterialia, 72, 362-370 (2018-03-22)
Poly(methyl methacrylate) (PMMA) is the most commonly used material for the treatment of osteoporosis-induced vertebral compression fractures. However, its high stiffness may introduce an increased risk of adjacent vertebral fractures post-surgery. One alternative in overcoming this concern is the use...
Philong Ta et al.
Journal of bacteriology, 193(8), 1981-1990 (2011-02-22)
The mshA::Tn5 mutant of Mycobacterium smegmatis does not produce mycothiol (MSH) and was found to markedly overproduce both ergothioneine and an ~15-kDa protein determined to be organic hydroperoxide resistance protein (Ohr). An mshA(G32D) mutant lacking MSH overproduced ergothioneine but not...
James E Dombrowski et al.
BMC research notes, 7, 807-807 (2014-11-19)
Previously it has been shown that mechanical wounding, salinity and heat activated a 46 kDa and 44 kDa mitogen-activated protein kinases (MAPKs) in forage related grasses. Forage and turf related grasses are utilized in diverse environments where they are routinely subjected to...
Laurent L'homme et al.
Journal of lipid research, 54(11), 2998-3008 (2013-09-06)
The NLRP3 inflammasome is involved in many obesity-associated diseases, such as type 2 diabetes, atherosclerosis, and gouty arthritis, through its ability to induce interleukin (IL)-1β release. The molecular link between obesity and inflammasome activation is still unclear, but free fatty...
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