Lysostaphin from Staphylococcus staphylolyticus

lyophilized powder, Protein 50-70 % by biuret, ≥500 units/mg protein

Glycyl-glycine Endopeptidase
Número CAS:
Número da licença da enzima:
Número MDL:

fonte biológica

microbial (Staphylococcus staphylotyticus)

Nível de qualidade



lyophilized powder

specific activity

≥500 units/mg protein

peso molecular

25 kDa


Protein, 50-70% biuret


pkg of (sold on basis of mg protein)


water: 2.00-2.10 mg/mL, clear to slightly hazy, colorless to light yellow

Setor em destaque

Diagnostic Assay Manufacturing
Diagnostic Assay Manufacturing

Modo de ação

cell wall synthesis | interferes

espectro de atividade do antibiótico

Gram-positive bacteria

enviado em

wet ice

temperatura de armazenamento


Procurando produtos similares? Visit Guia de comparação de produtos

Descrição geral

Chemical structure: peptide


1, 5, 15 mg in glass bottle

Ações bioquímicas/fisiológicas

Lysostaphin is a zinc endopeptidase with a molecular weight of approximately 25 kDa. Because lysostaphin cleaves the polyglycine cross-links in the peptidoglycan layer of the cell wall of Staphylococcus species it has been found useful for cell lysis and also as a potential anti-microbial therapeutic.
pH Optimum for activity: ~7.5

Definição da unidade

One unit will reduce the turbidity (A620) of a suspension of Staphylococcus aureus cells from 0.250 to 0.125 in 10 min at pH 7.5 at 37°C in a 6.0 ml reaction mixture.


Health hazard

Palavra indicadora


Frases de perigo

Declarações de precaução


Resp. Sens. 1


11 - Combustible Solids

WGK Alemanha


Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificado de análise

Certificado de origem

Lisbeth Drozd Lund et al.
PloS one, 11(2), e0149092-e0149092 (2016-02-13)
Staphylococcus aureus is a major human pathogen that has evolved very efficient immune evading strategies leading to persistent colonization. During different stages of growth, S. aureus express various surface molecules, which may affect the immune stimulating properties, but very little...
Ian R Monk et al.
Nature communications, 10(1), 3067-3067 (2019-07-13)
WalKR (YycFG) is the only essential two-component regulator in the human pathogen Staphylococcus aureus. WalKR regulates peptidoglycan synthesis, but this function alone does not explain its essentiality. Here, to further understand WalKR function, we investigate a suppressor mutant that arose...
Judy J J Ou et al.
Frontiers in cellular and infection microbiology, 6, 187-187 (2017-01-14)
Background:Staphylococcus aureus (S. aureus) small colony variants (SCVs) can survive within the host intracellular milieu and are associated with chronic relapsing infections. However, it is unknown whether host invasion rates and immune responses differ between SCVs and their wild-type counterparts....
Catherine Bennett et al.
International forum of allergy & rhinology, 9(8), 918-925 (2019-06-05)
Chronic rhinosinusitis (CRS) is a common disease, often refractory to conventional antimicrobial treatment. In this study we investigate the antimicrobial and anti-inflammatory effects of adding kappa-carrageenan to a commercially available sinus rinse. Kappa-carrageenan was added to Flo CRS and Flo...
Igor Belyansky et al.
The Journal of surgical research, 171(2), 409-415 (2011-06-24)
Lysostaphin (LS), a naturally occurring Staphylococcal endopeptidase, has the ability to penetrate biofilm, and has been identified as a potential antimicrobial to prevent mesh infection. The goals of this study were to determine if LS adhered to porcine mesh (PM)...
GenElute™ Bacterial Genomic DNA Kit protocol describes a simple and convenient way for the isolation of pure genomic DNA from bacteria.
Leia mais

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica