L7527
Lipoprotein, very low density from human plasma
≥95% (SDS-PAGE), solution
Sinônimo(s):
Pre-β-lipoprotein, VLDL, Very low density lipoprotein
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Estamos aqui para ajudarNome do produto
Lipoprotein, very low density from human plasma, ≥95% (SDS-PAGE), solution
biological source
human plasma
assay
≥95% (SDS-PAGE)
form
solution
functional group
ester
phospholipid
shipped in
wet ice
storage temp.
2-8°C
Quality Level
Gene Information
human ... APOB(338), APOC2(344), APOE(348)
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Other Notes
View more information on lipoprotein function and lipid transport at www.sigma-aldrich.com/enzymeexplorer
Physical form
Solution in 150 mM NaCl and 0.01% EDTA, pH 7.4
Biochem/physiol Actions
Inhibits DNA synthesis in lymphocytes activated by the nonspecific mitogen concanavalin A (Con A).
VLDL (Very low density lipoprotein) may be used to study the mechanisms and effects of very low density receptors (VLDLR). VLDL is used as a potential source of fatty acids that support cardiac energy metabolism. VLDL is often studied to differentiate its effects from those of chylomicrons.
Classe de armazenamento
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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Akifumi Kushiyama et al.
Arteriosclerosis, thrombosis, and vascular biology, 33(8), 1986-1993 (2013-05-25)
Resistin-like molecule (RELM) β is a secretory protein homologous to resistin and reportedly contributes to local immune response regulation in gut and bronchial epithelial cells. However, we found that activated macrophages also express RELMβ and thus investigated the role of
Matthew R Sobansky et al.
Analytical and bioanalytical chemistry, 406(25), 6203-6211 (2014-08-12)
High-performance affinity chromatography (HPAC) was utilized to examine the binding of very low density lipoprotein (VLDL) with drugs, using R/S-propranolol as a model. These studies indicated that two mechanisms existed for the binding of R- and S-propranolol with VLDL. The
You-Guo Niu et al.
Journal of lipids, 2011, 189876-189876 (2011-07-21)
The heart is a major consumer of energy and is able to utilise a wide range of substrates including lipids. Nonesterified fatty acids (NEFA) were thought to be a favoured carbon source, but their quantitative contribution is limited because of
Katsuyuki Nakajima et al.
Clinica chimica acta; international journal of clinical chemistry, 412(15-16), 1306-1318 (2011-05-03)
Since Zilversmit first proposed postprandial lipemia as the most common risk of cardiovascular disease, chylomicrons (CM) and CM remnants have been thought to be the major lipoproteins which are increased in the postprandial hyperlipidemia. However, it has been shown over
Gwang-Woong Go et al.
The Yale journal of biology and medicine, 85(1), 19-28 (2012-03-31)
The LDLR family of proteins is involved in lipoproteins trafficking. While the role of LDLR in cardiovascular disease has been widely studied, only recently the role of other members of the LDLR proteins in lipoprotein homeostasis and atherosclerosis has emerged.
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