Merck
Todas as fotos(6)

L8000

Sigma-Aldrich

L-Leucine

reagent grade, ≥98% (HPLC)

Sinônimo(s):
(S)-2-Amino-4-methylpentanoic acid
Fórmula linear:
(CH3)2CHCH2CH(NH2)CO2H
Número CAS:
Peso molecular:
131.17
Beilstein:
1721722
Número EC:
Número MDL:
eCl@ss:
32160406
ID de substância PubChem:
NACRES:
NA.26

Nível de qualidade

200

grau

reagent grade

teor

≥98% (HPLC)

forma

powder

technique(s)

ligand binding assay: suitable

Impurezas

isoleucine and methionine, essentially free

cor

white to off-white

pf

>300 °C (lit.)

application(s)

peptide synthesis

SMILES string

CC(C)C[C@H](N)C(O)=O

InChI

1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1

InChI key

ROHFNLRQFUQHCH-YFKPBYRVSA-N

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Aplicação

L-Leucine has been used as an agonist of mechanistic target of rapamycin (mTOR) to determine whether AMPK/mTOR pathway is involved in berberine-mediated autophagy in J774A.1 cells. It has also been used for the selection of transformed cells.

Embalagem

25, 50, 100, 250 g in poly bottle
1 kg in poly bottle

Ações bioquímicas/fisiológicas

Leucine is a non-glucogenic, essential amino acid. It is a branched-chain amino acid that is a structural component of proteins. Leucine positively influences insulin release to eliminate toxic sugars out of the blood. The degradation of leucine leads to the formation of ketone bodies.

Código de classe de armazenamento

11 - Combustible Solids

WGK

WGK 1

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificado de análise

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Certificado de origem

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Dr. Victor Prisk
The Leucine Factor Diet: The Scientifically-Proven Approach to Combat Sugar, Burn Fat and Build Muscle (2015)
Berberine alleviates ox-LDL induced inflammatory factors by up-regulation of autophagy via AMPK/mTOR signaling pathway
Xiaodi Fan
Journal of Translational Medicine (2015)
Susan A Masino
Ketogenic Diet and Metabolic Therapies: Expanded Roles in Health and Disease (2016)
Markerless Gene Editing in the Hyperthermophilic Archaeon Thermococcus kodakarensis
Alexandra m
Bio-protocol (2017)
Sergio R Santa Maria et al.
Astrobiology (2020-01-07)
The biological risks of the deep space environment must be elucidated to enable a new era of human exploration and scientific discovery beyond low earth orbit (LEO). There is a paucity of deep space biological missions that will inform us

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