N3412

Sigma-Aldrich

Monoclonal Anti-Neuropilin-2 antibody produced in mouse

clone 96009, purified immunoglobulin, lyophilized powder

Número MDL:
NACRES:
NA.41

Nível de qualidade

100

fonte biológica

mouse

forma do anticorpo

purified immunoglobulin

antibody product type

primary antibodies

clone

96009, monoclonal

forma

lyophilized powder

species reactivity

rat

aplicação(ões)

indirect ELISA: 0.5-1 μg/mL using rrNeuropilin-2 extracellular domain
western blot: 1-2 μg/mL using rrNeuropilin-2 extracellular domain

Isotipo

IgG2b

conjugado

unconjugated

nº de adesão UniProt

enviado em

wet ice

temperatura de armazenamento

−20°C

Gene Information

rat ... Nrp2(81527)

Descrição geral

Neuropilin-2 (NRP-2) is expressed in the neurons of the developing nervous system in rats.

Especificidade

Shows no cross-reactivity with human neuropilin-1.

Imunogênio

purified, NS0-derived, recombinant rat neuropilin-2 extracellular domain.

Ações bioquímicas/fisiológicas

Neuropilin-2 (NRP-2) is involved in assembly of Schwann cells into aggregates, which have a role in the regeneration of neurons.

forma física

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

storage_class_code

13 - Non Combustible Solids

WGK Alemanha

WGK 3

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificado de análise

Certificado de origem

Gera Neufeld et al.
Advances in experimental medicine and biology, 515, 81-90 (2003-03-05)
The Neuropilin-1 (NRP1) and Neuropilin-2 (NRP2) receptors were initially described as receptors for axon guidance factors belonging to the class-3 Semaphorin sub-family. Subsequently, it was found the Neuropilins also function as receptors for some forms of vascular endothelial growth factor...
J Ara et al.
Journal of neuroscience research, 79(4), 468-475 (2005-01-07)
Neuropilins and group A plexins are components of receptor complexes for class 3 semaphorins, gradients of which help to guide migration of neural progenitor cells and axonal growth cones during development. We demonstrated previously that neuropilins and class 3 semaphorins...
A L Kolodkin et al.
Cell, 90(4), 753-762 (1997-08-22)
The semaphorin family contains a large number of phylogenetically conserved proteins and includes several members that have been shown to function in repulsive axon guidance. Semaphorin III (Sema III) is a secreted protein that in vitro causes neuronal growth cone...

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